Cheap flights from Des Moines to Santa Ana from £80

A one-way nonstop (direct) flight between Des Moines and Santa Ana takes around 3.8 hours.

The flight distance between Des Moines and Santa Ana is 2297 km.

Several carriers operate flights between Des Moines and Santa Ana. Airlines offering nonstop (direct) flights include Allegiant Air.

Travelers frequently search for route combinations, such as Des Moines and Las Vegas, Nashville, Phoenix, Istanbul, Austin, Orlando, Guadalajara, Tampa, Houston, Sarasota, Shanghai, Winnipeg, Montreal, Kathmandu, Punta Gorda, Malé, Boston, Monrovia, Mexico City, Vancouver.

Travelers frequently search for route combinations, such as Santa Ana and Provo, Calgary, Las Vegas, San Francisco, Vancouver, London, Seattle, Phoenix, Oakland, Denver, Edmonton, Eugene, Boise, Colorado Springs, Hong Kong, Medford, Kelowna, Idaho Falls, Dallas, Istanbul.

The main airport in Des Moines is Des Moines International. It is also served by Des Moines International, Eppley Airfield, The Eastern Iowa, Mason City Municipal, Kirksville Regional, Fort Dodge Regional, Waterloo Regional, Southeast Iowa Regional, Sioux Gateway.

The main airport in Santa Ana is John Wayne. It is also served by Tijuana International, San Diego International, Ontario International, John Wayne, Palm Springs International, Hollywood Burbank, Santa Barbara Municipal, Imperial County, Long Beach, Hawthorne Municipal.

Currently, you can fly between Des Moines and Santa Ana with United Airlines, Allegiant Air, Frontier Airlines, Spirit Airlines, JetBlue Airways.

If you don’t have specific dates for your trip between Des Moines and Santa Ana, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.