San Diego — Des Moines flights are offered by 5 airline(s) including Delta Air Lines, Spirit Airlines, American Airlines, Southwest Airlines, United Airlines.
The cheapest one-way flights are usually available on a Thursday. The average price of a one-way flight is currently $ 147.84. The lowest price is $ 133.65 departing on local with Spirit Airlines. San Diego - SAN is the cheapest airport for flights San Diego — Des Moines.