San Diego — Des Moines flights are offered by 6 airline(s) including United Airlines, Delta Air Lines, American Airlines, Frontier Airlines, Southwest Airlines, Spirit Airlines.
The cheapest one-way flights are usually available on a Tuesday. The average price of a one-way flight is currently $ 143.36. The lowest price is $ 137.44 departing on local with Delta Air Lines. San Diego - SAN is the cheapest airport for flights San Diego — Des Moines.