San Diego — Des Moines flights are offered by 6 airline(s) including Southwest Airlines, Delta Air Lines, Spirit Airlines, American Airlines, Frontier Airlines, United Airlines.
The cheapest one-way flights are usually available on a Wednesday. The average price of a one-way flight is currently $ 152.72. The lowest price is $ 133.78 departing on local with Spirit Airlines. San Diego - SAN is the cheapest airport for flights San Diego — Des Moines.