Cheap flights from Santa Ana to San Luis Obispo from $249

Travelers frequently search for route combinations, such as Santa Ana and Provo, Las Vegas, Calgary, San Francisco, Vancouver, Phoenix, Oakland, Denver, Seattle, Boise, Edmonton, New York, Dallas, Medford, Idaho Falls, Portland, Lisbon, Des Moines, Sacramento, Grand Junction.

Travelers frequently search for route combinations, such as San Luis Obispo and Portland, Los Angeles, New York, Houston, Indianapolis, Pasco, Boston, San Jose, Salt Lake City, Ontario, Eugene, Reno, Nashville, Minneapolis, Kahului, Las Vegas, Atlanta, San Diego, El Paso, Chicago.

The main airport in Santa Ana is John Wayne. It is also served by Tijuana International, San Diego International, Ontario International, John Wayne, Palm Springs International, Hollywood Burbank, Santa Barbara Municipal, Long Beach, Hawthorne Municipal, McClellan–Palomar.

The main airport in San Luis Obispo is San Luis Obispo County Regional. It is also served by Fresno Yosemite International, Hollywood Burbank, San Luis Obispo County Regional, Monterey Regional, Santa Barbara Municipal, Santa Maria Public, Meadows Field.

Currently, you can fly between Santa Ana and San Luis Obispo with United Airlines, Alaska Airlines, Hawaiian Airlines, Spirit Airlines, WestJet.

If you don’t have specific dates for your trip between Santa Ana and San Luis Obispo, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Santa Ana and San Luis Obispo, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Santa Ana. The main one is John Wayne and other nearby airports include Tijuana International, San Diego International, Ontario International, John Wayne, Palm Springs International, Hollywood Burbank, Santa Barbara Municipal, Long Beach, Hawthorne Municipal, McClellan–Palomar

There are a number of airports in and around San Luis Obispo. The main one is San Luis Obispo County Regional and other nearby airports include Fresno Yosemite International, Hollywood Burbank, San Luis Obispo County Regional, Monterey Regional, Santa Barbara Municipal, Santa Maria Public, Meadows Field.