Cheap flights from St. Louis to San Diego from $68

Travelers frequently search for route combinations, such as St. Louis and Las Vegas, Cancún, Orlando, Los Angeles, San Francisco, Denver, Mexico City, Tuxtla Gutiérrez, Toronto, Ottawa, Lima, Buenos Aires, Cali, Sydney, Warsaw, San José, Washington, D.C., Reykjavik, Fort Lauderdale, Melbourne.

Travelers frequently search for route combinations, such as San Diego and San Francisco, San Jose, New York, Las Vegas, Sacramento, Calgary, London, Seattle, Phoenix, Dallas, Denver, Houston, Washington, D.C., Tokyo, Oakland, Chicago, Minneapolis, Honolulu, Vancouver, Portland.

The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, General Wayne A. Downing Peoria International, Evansville Regional, Waynesville-St. Robert Regional, Abraham Lincoln Capital, Cape Girardeau Regional, MidAmerica St. Louis, Barkley Regional, Williamson County Regional, Central Illinois Regional.

The main airport in San Diego is San Diego International. It is also served by Tijuana International, Ontario International, John Wayne, Palm Springs International, Mexicali International, Hollywood Burbank, Long Beach, Yuma International, Imperial County, Hawthorne Municipal.

Currently, you can fly between St. Louis and San Diego with United Airlines, Alaska Airlines, Frontier Airlines, Southern Airways Express, Hawaiian Airlines.

If you don’t have specific dates for your trip between St. Louis and San Diego, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between St. Louis and San Diego, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around St. Louis. The main one is St. Louis Lambert International and other nearby airports include St. Louis Lambert International, General Wayne A. Downing Peoria International, Evansville Regional, Waynesville-St. Robert Regional, Abraham Lincoln Capital, Cape Girardeau Regional, MidAmerica St. Louis, Barkley Regional, Williamson County Regional, Central Illinois Regional

There are a number of airports in and around San Diego. The main one is San Diego International and other nearby airports include Tijuana International, Ontario International, John Wayne, Palm Springs International, Mexicali International, Hollywood Burbank, Long Beach, Yuma International, Imperial County, Hawthorne Municipal.