Cheap flights from St. Louis to Santa Ana from $237

Travelers frequently search for route combinations, such as St. Louis and Orlando, Las Vegas, Fort Lauderdale, Los Angeles, London, San Juan, Cancún, Denver, Reno, Seattle, San Francisco, New York, Washington, D.C., Amsterdam, Medellín, Oakland, Burbank, Beirut, Calgary, Charlotte.

Travelers frequently search for route combinations, such as Santa Ana and Las Vegas, Phoenix, Denver, Provo, Seattle, Dallas, Portland, Minneapolis, Oakland, Austin, Boise, Reno, Cleveland, Sacramento, San Francisco, Salt Lake City, Oklahoma City, Nashville, Vancouver, New York.

The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, Evansville Regional, Abraham Lincoln Capital, General Wayne A. Downing Peoria International, MidAmerica St. Louis, Cape Girardeau Regional, University of Illinois Willard, Williamson County Regional, Barkley Regional, Central Illinois Regional.

The main airport in Santa Ana is John Wayne. It is also served by Tijuana International, San Diego International, John Wayne, Ontario International, Palm Springs International, Hollywood Burbank, Long Beach, Santa Barbara Municipal, Imperial County, Meadows Field.

Currently, you can fly between St. Louis and Santa Ana with United Airlines, Alaska Airlines, Hawaiian Airlines, American Airlines.

If you don’t have specific dates for your trip between St. Louis and Santa Ana, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between St. Louis and Santa Ana, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around St. Louis. The main one is St. Louis Lambert International and other nearby airports include St. Louis Lambert International, Evansville Regional, Abraham Lincoln Capital, General Wayne A. Downing Peoria International, MidAmerica St. Louis, Cape Girardeau Regional, University of Illinois Willard, Williamson County Regional, Barkley Regional, Central Illinois Regional

There are a number of airports in and around Santa Ana. The main one is John Wayne and other nearby airports include Tijuana International, San Diego International, John Wayne, Ontario International, Palm Springs International, Hollywood Burbank, Long Beach, Santa Barbara Municipal, Imperial County, Meadows Field.