Cheap flights from Mayagüez, United States to Madrid, Spain

Travelers frequently search for route combinations, such as Mayagüez and Washington, D.C., New York, Fort Lauderdale, Philadelphia, Boston, Denver, Madison, Atlanta, San Juan, Fayetteville, Orlando, Las Vegas, Chicago, Miami, Los Angeles, Mexico City, Bogotá, Dallas, Phoenix, San Francisco.

Travelers frequently search for route combinations, such as Madrid and New York, Los Angeles, Boston, San Francisco, Chicago, Miami, Denver, Orlando, London, Paris, Barcelona, Seattle, Atlanta, Caracas, Mexico City, Tel Aviv, Washington, D.C., Dallas, Raleigh, Houston.

The main airport in Mayagüez is Eugenio María de Hostos. It is also served by Luis Muñoz Marín International, Aguadilla Rafael Hernandez, Fernando Luis Ribas Dominicci, José Aponte de la Torre, Eugenio María de Hostos, Mercedita.

The main airport in Madrid is Adolfo Suárez Madrid–Barajas. It is also served by Valladolid, Salamanca.

Yes, it's possible to combine different modes of transport between Mayagüez and Madrid thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between Mayagüez and Madrid can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.

Virtual Interlining provides a revolutionary way of traveling. You can combine different modes of transport like flights, trains, and buses into one itinerary. And this often saves money. Thanks to the world's largest carrier database, the Kiwi.com search function enables anyone to mix and match different modes of transport easily.

Currently, you can fly between Mayagüez and Madrid with Cape Air, Iberia Airlines, Frontier Airlines, Air Europa, Avianca.

If you don’t have specific dates for your trip between Mayagüez and Madrid, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Mayagüez and Madrid, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What's more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.