Cheap flights from Medford to Des Moines from $399

Travelers frequently search for route combinations, such as Medford and Orlando, Las Vegas, Los Angeles, Phoenix, Puerto Escondido, Oaxaca, Portland, Santa Ana, London, Mexico City, Calgary, San Francisco, Dallas, Guatemala City, Springfield, Varna, Ontario, Guadalajara, San Antonio, Seville, Kansas City.

Travelers frequently search for route combinations, such as Des Moines and Los Angeles, Seattle, Washington, D.C., Las Vegas, Denver, Nashville, New York, Fort Lauderdale, Orlando, Boston, Idaho Falls, Santa Ana, Salt Lake City, Portland, Detroit, Sacramento, Kauai, Phoenix, Charleston, Burbank.

The main airport in Medford is Rogue Valley International–Medford. It is also served by Rogue Valley International–Medford, Eugene, Del Norte County, Redding Municipal, Southwest Oregon Regional.

The main airport in Des Moines is Des Moines International. It is also served by Eppley Airfield, Des Moines International, The Eastern Iowa, Fort Dodge Regional, Southeast Iowa Regional, Mason City Municipal, Waterloo Regional, Kirksville Regional, Sioux Gateway.

Currently, you can fly between Medford and Des Moines with American Airlines, Alaska Airlines, United Airlines.

If you don’t have specific dates for your trip between Medford and Des Moines, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Medford and Des Moines, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Medford. The main one is Rogue Valley International–Medford and other nearby airports include Rogue Valley International–Medford, Eugene, Del Norte County, Redding Municipal, Southwest Oregon Regional

There are a number of airports in and around Des Moines. The main one is Des Moines International and other nearby airports include Eppley Airfield, Des Moines International, The Eastern Iowa, Fort Dodge Regional, Southeast Iowa Regional, Mason City Municipal, Waterloo Regional, Kirksville Regional, Sioux Gateway.