Cheap flights from Rome to Charleston from $423

Travelers frequently search for route combinations, such as Rome and Los Angeles, New York, Orlando, San Francisco, Miami, Phoenix, Atlanta, Washington, D.C., Dallas, Boston, Paris, Charlotte, Las Vegas, Denver, Houston, Chicago, Nashville, London, Kansas City, San Juan.

Travelers frequently search for route combinations, such as Charleston and New York, Philadelphia, Tampa, Pittsburgh, Denver, Cincinnati, Orlando, Providence, Boston, San Diego, Phoenix, Las Vegas, Los Angeles, Houston, Hartford, Fort Lauderdale, Louisville, Syracuse, New Orleans, Westchester County.

Rome is mainly served by Leonardo da Vinci–Fiumicino Airport. But there are other airports nearby, including Ciampino–G. B. Pastine International.

The main airport in Rome is Leonardo da Vinci–Fiumicino Airport. It is also served by Naples International, Florence, Marche Airport, San Francesco d Assisi, Abruzzo.

The main airport in Charleston is Charleston International. It is also served by Charleston International, Myrtle Beach International, Savannah/Hilton Head International, Columbia Metropolitan, Augusta Regional, Hilton Head, Brunswick Golden Isles.

Currently, you can fly between Rome and Charleston with JetBlue Airways, BREEZE, Spirit Airlines, French Bee, ITA Airways.

If you don’t have specific dates for your trip between Rome and Charleston, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Rome and Charleston, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Rome. The main one is Leonardo da Vinci–Fiumicino Airport and other nearby airports include Naples International, Florence, Marche Airport, San Francesco d Assisi, Abruzzo