Cheap flights from Rome, Italy to San Francisco, CA

Flights starting at $346. Choose between American Airlines, Ryanair, or Vueling to find the best price.

Make your travel wishlist, we'll do the rest
Hidden deals
Effortless booking
Travel hacking

Tips to know when travelling to San Francisco

Mailbox
Receive exclusive deals by email
Travelers usually depart from Leonardo da Vinci–Fiumicino Airport, Ciampino–G. B. Pastine International, Roma - Termini, Roma - Tiburtina, or Rome - Anagnina when they travel from Rome to San Francisco. Book your trip to arrive at San Francisco International, San Francisco, CA Train Station, San Francisco, CA Bus Stop, or San Francisco, CA - Fisherman’s Wharf. The distance between Rome and San Francisco is 10069 km. The most popular airlines for this route are American Airlines, Ryanair, Vueling, Spirit Airlines, and Frontier Airlines. Rome and San Francisco have 283 direct flights per week. When you arrive at San Francisco, consider visiting Alcatraz, Big Sur, and Golden Gate Bridge.

Weekly direct flights

Discover the top airlines offering direct flights from Rome to San Francisco in the next month. You’ll find the number of daily direct flights per airline in the table.

Weekly direct flights for Sun 26.11 - Sat 02.12

AirlineSun 26.11Mon 27.11Tue 28.11Wed 29.11Thu 30.11Fri 01.12Sat 02.12
------1---------1

Weekly direct flights for Sun 03.12 - Sat 09.12

AirlineSun 03.12Mon 04.12Tue 05.12Wed 06.12Thu 07.12Fri 08.12Sat 09.12
------------1---1

Weekly direct flights for Sun 10.12 - Sat 16.12

AirlineSun 10.12Mon 11.12Tue 12.12Wed 13.12Thu 14.12Fri 15.12Sat 16.12
------1---1---1

Weekly direct flights for Sun 17.12 - Sat 23.12

AirlineSun 17.12Mon 18.12Tue 19.12Wed 20.12Thu 21.12Fri 22.12Sat 23.12
------1---1---1

Check-in for a flight from Rome to San Francisco

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
American AirlinesAALAANoNo
RyanairRYRFRNoOpens 24 days before flight
Closes 2 hours before flight
VuelingVLGVYNoOpens 168 days before flight
Closes 4 hours before flight
Spirit AirlinesNKSNKNoOpens 24 days before flight
Closes 1 hours before flight
Frontier AirlinesFFTF9NoOpens 24 days before flight
Closes 1 hours before flight

United States COVID-19 travel restrictions

Your trip summary

Departure

Travel restrictions
  • Travel is allowed
  • Proof of pre-departure COVID-19 test is not required
  • Quarantine is not required
Visa requirements
  • Electronic Travel Authorization (ESTA)

Return

Travel restrictions
  • Travel is allowed
  • Proof of pre-departure COVID-19 test is not required
  • Quarantine is not required
Visa requirements
  • Electronic Travel Authorization (ESTA)

Frequently asked questions

What is the flight distance between Rome and San Francisco?
What airlines offer nonstop (direct) flights between Rome and San Francisco?
What are the most popular routes to and from Rome?
What are the most popular routes to and from San Francisco?
Which airports are there in Rome?
What airports are near Rome?
What airports are near San Francisco?
What buses and trains depart from Rome?
Is it possible to combine flights, buses, and trains in one itinerary when traveling between Rome and San Francisco?
What is Virtual Interlining and how do I use it?
Which airlines fly between Rome and San Francisco?
When's the best time to travel between Rome and San Francisco?
What flights operate between Rome and San Francisco?
How many airports are there near Rome?
How many airports are there near San Francisco?
Is it possible to reach Rome by bus or train?
What time do nonstop (direct) flights between Rome and San Francisco depart?
What time do nonstop (direct) flights between Rome and San Francisco arrive?
What time do flights between Rome and San Francisco depart?
What time do flights between Rome and San Francisco arrive?

Explore alternative trips

Flights from Rome

Flights to San Francisco

Popular routes

Find the best connection from Rome to San Francisco
Search flights, trains & buses

We hack the system,
you fly for less