Cheap flights from San Luis Obispo to Santa Cruz de la Sierra from $563

Travelers frequently search for route combinations, such as San Luis Obispo and Seattle, Puerto Vallarta, Portland, Denver, Spokane, Columbus, Palm Springs, Detroit, Omaha, Sylhet, Tijuana, Cúcuta, Tirana, Honolulu, Saint Thomas, Puerto Escondido, Oaxaca, Norfolk, Indianapolis, Madrid, St. Louis.

Travelers frequently search for route combinations, such as Santa Cruz de la Sierra and La Paz, Miami, Cochabamba, New York, Washington, D.C., Sucre, Los Angeles, Charlotte, Tarija, Uyuni, Santiago de Chile, Trinidad, Bogotá, Lima, Panama, Buenos Aires, Madrid, Rio de Janeiro, Guadalajara, Moline.

The main airport in San Luis Obispo is San Luis Obispo County Regional. It is also served by Fresno Yosemite International, Hollywood Burbank, Monterey Regional, San Luis Obispo County Regional, Santa Barbara Municipal, Santa Maria Public, Meadows Field.

Currently, you can fly between San Luis Obispo and Santa Cruz de la Sierra with Hawaiian Airlines, Copa Airlines, LATAM Airlines, Avianca, Boliviana de Aviación.

If you don’t have specific dates for your trip between San Luis Obispo and Santa Cruz de la Sierra, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between San Luis Obispo and Santa Cruz de la Sierra, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around San Luis Obispo. The main one is San Luis Obispo County Regional and other nearby airports include Fresno Yosemite International, Hollywood Burbank, Monterey Regional, San Luis Obispo County Regional, Santa Barbara Municipal, Santa Maria Public, Meadows Field

This depends on the airline’s flight schedule. You can easily select your preferred departure time when you search on our website or mobile app. Choose the time of day you wish to depart from San Luis Obispo, such as morning, afternoon, evening, or night, or select the exact hours for departure.

This depends on the airline’s flight schedule. You can easily select your preferred arrival time when you search on our website or mobile app. Choose the time of day you wish to arrive at Santa Cruz de la Sierra, such as morning, afternoon, evening, or night, or select the exact hours for arrival.