Cheap flights from Panama City to Santa Cruz de la Sierra from $470

A one-way nonstop (direct) flight between Panama and Santa Cruz de la Sierra takes around 5.0 hours.

The flight distance between Panama and Santa Cruz de la Sierra is 3469 km.

Several carriers operate flights between Panama and Santa Cruz de la Sierra. Airlines offering nonstop (direct) flights include Copa Airlines.

Travelers frequently search for route combinations, such as Panama and Bocas Town, Bocas del Toro, Miami, New York, Washington, D.C., Houston, Denver, Boston, Atlanta, Minneapolis, David, Chiriquí, Los Angeles, Asheville, Detroit, Dallas, Tampa, Orlando, Medellín, Las Vegas, San Juan, Raleigh.

Travelers frequently search for route combinations, such as Santa Cruz de la Sierra and Washington, D.C., New York, Houston, Atlanta, Austin, Chicago, Tampa, Los Angeles, Denver, Minneapolis, Anchorage, Miami, Boston, La Paz, Sucre, Madrid, Cochabamba, Rio de Janeiro, São Paulo, Lima.

Panama is mainly served by Tocumen International. But there are other airports nearby, including Albrook Marcos A. Gelabert International.

Currently, you can fly between Panama and Santa Cruz de la Sierra with Copa Airlines, Boliviana de Aviación, Avianca, LATAM Airlines, Wingo airlines.

If you don’t have specific dates for your trip between Panama and Santa Cruz de la Sierra, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Panama and Santa Cruz de la Sierra, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.