Find cheap flights to Tupelo from $167

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2 stops

Tue, Oct 28

Columbus CMHTupelo TUP

$167

2 stops

Tue, Oct 28

Columbus CMHTupelo TUP

$167

2 stops

Sun, Oct 26

Columbus CMHTupelo TUP

$169

2 stops

Sun, Oct 26

Columbus CMHTupelo TUP

$174

2 stops

Sun, Oct 26

Columbus CMHTupelo TUP

$185

2 stops

Sun, Oct 26

Columbus CMHTupelo TUP

$211

Prices updated: 10/06/2025

2 stops

Tue, Oct 28 – Thu, Oct 30

Columbus CMHTupelo TUP

$333

2 stops

Sun, Oct 26 – Thu, Oct 30

Columbus CMHTupelo TUP

$340

2 stops

Wed, Oct 29 – Sat, Nov 1

Columbus CMHTupelo TUP

$371

2 stops

Wed, Oct 29 – Sat, Nov 1

Columbus CMHTupelo TUP

$371

2 stops

Wed, Oct 29 – Sat, Nov 1

Columbus CMHTupelo TUP

$371

2 stops

Sun, Oct 26 – Thu, Oct 30

Columbus CMHTupelo TUP

$377

Prices updated: 10/06/2025

Cheap flights to Tupelo

Weather in Tupelo

Average Weather

Month	Average monthly max temperature	Average monthly min temperature
January	9°C	1°C
February	12°C	3°C
March	17°C	7°C
April	22°C	11°C
May	26°C	16°C
June	31°C	20°C
July	32°C	22°C
August	32°C	21°C
September	29°C	18°C
October	23°C	12°C
November	16°C	6°C
December	12°C	4°C