Cheap flights from Appleton to Des Moines from $138

Travelers frequently search for route combinations, such as Appleton and Phoenix, Punta Gorda, Tampa, Fort Lauderdale, Nashville, Orlando, Sarasota, Savannah, Puebla, Birmingham, Louisville, Oakland, Bangor, Bratislava, Bismarck, Kabul, Chiang Mai, Riyadh, Kalispell, Montevideo.

Travelers frequently search for route combinations, such as Des Moines and Nashville, Fort Lauderdale, Las Vegas, Phoenix, Austin, Santa Ana, Denver, New York, London, Los Angeles, Portland, Peoria, Orlando, Guadalajara, Mexico City, Mobile, South Bend, Ontario, Seattle, Jackson.

The main airport in Appleton is Appleton International. It is also served by General Mitchell International, Appleton International, Chicago Rockford International, Dane County Regional, Green Bay–Austin Straubel International, Central Wisconsin, Ford, Delta County, Rhinelander–Oneida County, La Crosse Regional.

The main airport in Des Moines is Des Moines International. It is also served by Des Moines International, Eppley Airfield, The Eastern Iowa, Mason City Municipal, Kirksville Regional, Fort Dodge Regional, Waterloo Regional, Southeast Iowa Regional, Sioux Gateway.

Currently, you can fly between Appleton and Des Moines with United Airlines, Allegiant Air, Frontier Airlines, Spirit Airlines.

If you don’t have specific dates for your trip between Appleton and Des Moines, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Appleton and Des Moines, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Appleton. The main one is Appleton International and other nearby airports include General Mitchell International, Appleton International, Chicago Rockford International, Dane County Regional, Green Bay–Austin Straubel International, Central Wisconsin, Ford, Delta County, Rhinelander–Oneida County, La Crosse Regional

There are a number of airports in and around Des Moines. The main one is Des Moines International and other nearby airports include Des Moines International, Eppley Airfield, The Eastern Iowa, Mason City Municipal, Kirksville Regional, Fort Dodge Regional, Waterloo Regional, Southeast Iowa Regional, Sioux Gateway.