Charleston, SC to Indianapolis, IN flights

Travelers frequently search for route combinations, such as Charleston and Denver, Las Vegas, Pittsburgh, Cincinnati, Cleveland, Philadelphia, Los Angeles, London, San Francisco, Nashville, Salt Lake City, Austin, Chicago, New York, Amsterdam, Madrid, New Orleans, Paris, Orlando, San Diego.

Travelers frequently search for route combinations, such as Indianapolis and Las Vegas, Orlando, Denver, Los Angeles, Fort Lauderdale, Austin, Phoenix, San Francisco, San Diego, Jacksonville, Salt Lake City, Atlanta, West Palm Beach, Sacramento, Portland, Tampa, Washington, D.C., Houston, Philadelphia, Seattle.

The main airport in Charleston is Charleston International. It is also served by Charleston International, Myrtle Beach International, Savannah/Hilton Head International, Columbia Metropolitan, Augusta Regional, Florence Regional, Hilton Head, Brunswick Golden Isles.

The main airport in Indianapolis is Indianapolis International. It is also served by Cincinnati/Northern Kentucky International, Indianapolis International, Louisville International, Blue Grass, Dayton International, Fort Wayne International, South Bend International, Owensboro–Daviess County Regional, Central Illinois Regional, Decatur.

A number of bus and train companies depart from Charleston, including Amtrak train.

Yes, it's possible to combine different modes of transport between Charleston and Indianapolis thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between Charleston and Indianapolis can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.

Virtual Interlining provides a revolutionary way of traveling. You can combine different modes of transport like flights, trains, and buses into one itinerary. And this often saves money. Thanks to the world's largest carrier database, the Kiwi.com search function enables anyone to mix and match different modes of transport easily.

Currently, you can fly between Charleston and Indianapolis with American Airlines, Spirit Airlines, United Airlines, Frontier Airlines, JetBlue Airways.

If you don’t have specific dates for your trip between Charleston and Indianapolis, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.