Cheap flights from Detroit to Des Moines from $159

Travelers frequently search for route combinations, such as Detroit and Mexico City, Guadalajara, Orlando, Atlanta, New York, Dallas, Monterrey, Baghdad, Erbil, Philadelphia, Tampa, Phoenix, Fort Myers, Los Angeles, Santiago de Querétaro, Cancún, Denver, Las Vegas, Washington, D.C., Istanbul.

Travelers frequently search for route combinations, such as Des Moines and Nashville, Fort Lauderdale, Las Vegas, Phoenix, Austin, Santa Ana, Denver, New York, London, Los Angeles, Portland, Peoria, Orlando, Guadalajara, Mexico City, Mobile, South Bend, Ontario, Seattle, Jackson.

Detroit is mainly served by Detroit Metropolitan. But there are other airports nearby, including Coleman A. Young Municipal Airport, Willow Run Airport.

The main airport in Detroit is Detroit Metropolitan. It is also served by Cleveland Hopkins International, Akron–Canton, Gerald R. Ford International, Bishop International, Fort Wayne International, Capital Region International, Toledo Express, London International, Windsor International, MBS International.

The main airport in Des Moines is Des Moines International. It is also served by Des Moines International, Eppley Airfield, The Eastern Iowa, Southeast Iowa Regional, Kirksville Regional, Sioux Gateway, Fort Dodge Regional, Mason City Municipal, Waterloo Regional.

Currently, you can fly between Detroit and Des Moines with Allegiant Air, Spirit Airlines, United Airlines, Frontier Airlines, JetBlue Airways.

If you don’t have specific dates for your trip between Detroit and Des Moines, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Detroit and Des Moines, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Detroit. The main one is Detroit Metropolitan and other nearby airports include Cleveland Hopkins International, Akron–Canton, Gerald R. Ford International, Bishop International, Fort Wayne International, Capital Region International, Toledo Express, London International, Windsor International, MBS International