Cheap flights from Detroit to San Luis Obispo from $313

Travelers frequently search for route combinations, such as Detroit and Mexico City, Guadalajara, Orlando, Atlanta, New York, Dallas, Monterrey, Baghdad, Erbil, Philadelphia, Tampa, Phoenix, Fort Myers, Los Angeles, Santiago de Querétaro, Cancún, Denver, Las Vegas, Washington, D.C., Istanbul.

Travelers frequently search for route combinations, such as San Luis Obispo and Portland, Los Angeles, New York, Houston, Indianapolis, Pasco, Boston, San Jose, Salt Lake City, Ontario, Eugene, Reno, Nashville, Minneapolis, Kahului, Las Vegas, Atlanta, San Diego, El Paso, Chicago.

The main airport in Detroit is Detroit Metropolitan. It is also served by Cleveland Hopkins International, Akron–Canton, Gerald R. Ford International, Bishop International, Fort Wayne International, Capital Region International, Toledo Express, London International, Windsor International, MBS International.

The main airport in San Luis Obispo is San Luis Obispo County Regional. It is also served by Fresno Yosemite International, Hollywood Burbank, Santa Barbara Municipal, Monterey Regional, Santa Maria Public, San Luis Obispo County Regional, Meadows Field.

Currently, you can fly between Detroit and San Luis Obispo with Alaska Airlines, WestJet, United Airlines, Air Canada, Porter Airlines.

If you don’t have specific dates for your trip between Detroit and San Luis Obispo, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Detroit and San Luis Obispo, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Detroit. The main one is Detroit Metropolitan and other nearby airports include Cleveland Hopkins International, Akron–Canton, Gerald R. Ford International, Bishop International, Fort Wayne International, Capital Region International, Toledo Express, London International, Windsor International, MBS International

There are a number of airports in and around San Luis Obispo. The main one is San Luis Obispo County Regional and other nearby airports include Fresno Yosemite International, Hollywood Burbank, Santa Barbara Municipal, Monterey Regional, Santa Maria Public, San Luis Obispo County Regional, Meadows Field.