Cheap flights from Knoxville to Muscle Shoals from $288

Travelers frequently search for route combinations, such as Knoxville and Fort Lauderdale, Houston, Orlando, Tampa, Phoenix, Denver, Buenos Aires, Mexico City, Boston, Berlin, Belleville, Toronto, Ahmedabad, Destin, Seoul, Bucharest, Casablanca, Tehran, Reykjavik, Chicago.

Travelers frequently search for route combinations, such as Muscle Shoals and Des Moines, Huntsville, Milwaukee, Albuquerque, Nashville, Atlanta, Cincinnati, Boston, Los Angeles, Charlotte, Kansas City, Austin, Santa Ana, Columbus, Houston, Philadelphia, San Antonio, Detroit, Chicago, Charleston.

The main airport in Knoxville is McGhee Tyson. It is also served by Nashville International, Asheville Regional, McGhee Tyson, Greenville–Spartanburg International, Blue Grass, Chattanooga Metropolitan, Tri-Cities Regional.

The main airport in Muscle Shoals is Northwest Alabama Regional. It is also served by Nashville International, Memphis International, Huntsville International, Chattanooga Metropolitan, Birmingham-Shuttlesworth International, Tupelo Regional, McKellar–Sipes Regional, Northwest Alabama Regional, Golden Triangle Regional.

Currently, you can fly between Knoxville and Muscle Shoals with Frontier Airlines, Allegiant Air, United Airlines, Air Canada.

If you don’t have specific dates for your trip between Knoxville and Muscle Shoals, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Knoxville and Muscle Shoals, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Knoxville. The main one is McGhee Tyson and other nearby airports include Nashville International, Asheville Regional, McGhee Tyson, Greenville–Spartanburg International, Blue Grass, Chattanooga Metropolitan, Tri-Cities Regional

There are a number of airports in and around Muscle Shoals. The main one is Northwest Alabama Regional and other nearby airports include Nashville International, Memphis International, Huntsville International, Chattanooga Metropolitan, Birmingham-Shuttlesworth International, Tupelo Regional, McKellar–Sipes Regional, Northwest Alabama Regional, Golden Triangle Regional.