Cheap flights from Louisville to San Diego from $144

Travelers frequently search for route combinations, such as Louisville and Fort Lauderdale, Los Angeles, Orlando, Charleston, Guatemala City, San Francisco, Fort Myers, Tampa, New York, Chicago, Mashhad, Raleigh, Santo Domingo, New Orleans, Paris, Porto, London, Sarasota, Erie, Concord.

Travelers frequently search for route combinations, such as San Diego and San Francisco, San Jose, New York, Las Vegas, Sacramento, Calgary, London, Seattle, Phoenix, Dallas, Denver, Houston, Washington, D.C., Tokyo, Oakland, Chicago, Minneapolis, Honolulu, Vancouver, Portland.

The main airport in Louisville is Louisville International. It is also served by Cincinnati/Northern Kentucky International, Indianapolis International, Louisville International, Blue Grass, Dayton International, Evansville Regional, Owensboro–Daviess County Regional.

The main airport in San Diego is San Diego International. It is also served by Tijuana International, John Wayne, Ontario International, Hollywood Burbank, Mexicali International, Palm Springs International, Long Beach, Imperial County, Hawthorne Municipal, Yuma International.

Currently, you can fly between Louisville and San Diego with United Airlines, BREEZE, Frontier Airlines, JetBlue Airways, Allegiant Air.

If you don’t have specific dates for your trip between Louisville and San Diego, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Louisville and San Diego, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Louisville. The main one is Louisville International and other nearby airports include Cincinnati/Northern Kentucky International, Indianapolis International, Louisville International, Blue Grass, Dayton International, Evansville Regional, Owensboro–Daviess County Regional

There are a number of airports in and around San Diego. The main one is San Diego International and other nearby airports include Tijuana International, John Wayne, Ontario International, Hollywood Burbank, Mexicali International, Palm Springs International, Long Beach, Imperial County, Hawthorne Municipal, Yuma International.