Cheap flights from Manchester to San Francisco from $221

Travelers frequently search for route combinations, such as Manchester and Orlando, Fort Myers, Charleston, Tampa, Philadelphia, Kuwait City, Dubai, Dallas, Hyderabad, Chicago, Daytona Beach, São Paulo, Rio de Janeiro, Raleigh, Mexico City, Manila, Sacramento, Frankfurt, Phoenix, Grand Rapids.

Travelers frequently search for route combinations, such as San Francisco and New York, Los Angeles, Mexico City, London, San Diego, Calgary, Las Vegas, Chicago, Tokyo, Burbank, Seoul, Barcelona, Phoenix, Seattle, New Delhi, Portland, Boston, Vancouver, Denver, Paris.

The main airport in Manchester is Manchester–Boston Regional. It is also served by Logan International, Bradley International, Rhode Island T. F. Green Int'l Airport, Albany International, Tweed New Haven, Manchester–Boston Regional, Portland International Jetport, Burlington International, Portsmouth International Airport at Pease, Knox County Regional.

The main airport in San Francisco is San Francisco International. It is also served by San Francisco International, Sacramento International, San Jose International, Oakland International, Stockton Metropolitan, Monterey Regional, Charles M. Schulz–Sonoma County, Merced Regional.

Currently, you can fly between Manchester and San Francisco with BREEZE, Frontier Airlines, United Airlines, JetBlue Airways, Spirit Airlines.

If you don’t have specific dates for your trip between Manchester and San Francisco, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Manchester and San Francisco, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Manchester. The main one is Manchester–Boston Regional and other nearby airports include Logan International, Bradley International, Rhode Island T. F. Green Int'l Airport, Albany International, Tweed New Haven, Manchester–Boston Regional, Portland International Jetport, Burlington International, Portsmouth International Airport at Pease, Knox County Regional

There are a number of airports in and around San Francisco. The main one is San Francisco International and other nearby airports include San Francisco International, Sacramento International, San Jose International, Oakland International, Stockton Metropolitan, Monterey Regional, Charles M. Schulz–Sonoma County, Merced Regional.