Cheap flights from Manchester to Chicago from $427

Travelers frequently search for route combinations, such as Manchester and New York, Miami, Boston, Washington, D.C., San Francisco, Honolulu, Cleveland, Atlanta, Seattle, Phoenix, Orlando, Raleigh, Los Angeles, Tel Aviv, Istanbul, Jeddah, Marrakesh, Dubai, Erbil, Oslo.

Travelers frequently search for route combinations, such as Chicago and Mexico City, New York, Guadalajara, Dallas, Houston, Atlanta, Los Angeles, Morelia, Orlando, Philadelphia, León, Tampa, San Francisco, Miami, Denver, Phoenix, Seattle, Monterrey, Las Vegas, Washington, D.C..

The main airport in Manchester is Manchester. It is also served by London Stansted, Manchester, Luton, Birmingham, Bristol, Liverpool John Lennon, Newcastle, Leeds Bradford, East Midlands, Cardiff.

The main airport in Chicago is O Hare International. It is also served by Gerald R. Ford International, South Bend International, Fort Wayne International, General Mitchell International, Dane County Regional, Quad City International, General Wayne A. Downing Peoria International, Central Illinois Regional, Muskegon County, University of Illinois Willard.

Currently, you can fly between Manchester and Chicago with Ryanair, Spirit Airlines, TAP Portugal, Frontier Airlines, easyJet.

If you don’t have specific dates for your trip between Manchester and Chicago, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Manchester and Chicago, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Manchester. The main one is Manchester and other nearby airports include London Stansted, Manchester, Luton, Birmingham, Bristol, Liverpool John Lennon, Newcastle, Leeds Bradford, East Midlands, Cardiff

There are a number of airports in and around Chicago. The main one is O Hare International and other nearby airports include Gerald R. Ford International, South Bend International, Fort Wayne International, General Mitchell International, Dane County Regional, Quad City International, General Wayne A. Downing Peoria International, Central Illinois Regional, Muskegon County, University of Illinois Willard.