Cheap flights from Mytilene to Istanbul from $144

Travelers frequently search for route combinations, such as Mytilene and Tel Aviv, Athens, Amsterdam, Malta, Cologne, Lamezia Terme, Heraklion, Mykonos, Frankfurt, Madrid, Zürich, Lisbon, Brussels, Thessaloniki, Paris, Ljubljana, Atlanta, London, Budapest, Berlin.

Travelers frequently search for route combinations, such as Istanbul and New York, Miami, Chicago, Los Angeles, Orlando, Washington, D.C., Boston, Las Vegas, San Francisco, Houston, Dallas, Atlanta, Detroit, Seattle, Tampa, Minneapolis, Phoenix, Raleigh, Denver, London.

The main airport in Mytilene is Mytilene International. It is also served by Mytilene International, Balıkesir Koca Seyit, Çanakkale, Chios Island National.

The main airport in Istanbul is Istanbul Airport. It is also served by Anadolu, Yenişehir, Tekirdağ Çorlu.

Currently, you can fly between Mytilene and Istanbul with Aegean, Pegasus, SKY express, Ryanair, Turkish Airlines.

If you don’t have specific dates for your trip between Mytilene and Istanbul, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Mytilene and Istanbul, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Mytilene. The main one is Mytilene International and other nearby airports include Mytilene International, Balıkesir Koca Seyit, Çanakkale, Chios Island National

There are a number of airports in and around Istanbul. The main one is Istanbul Airport and other nearby airports include Anadolu, Yenişehir, Tekirdağ Çorlu.