Cheap flights from Panama City to Santiago de los Caballeros from $294

Travelers frequently search for route combinations, such as Panama and Bocas Town, Bocas del Toro, Miami, New York, Los Angeles, Washington, D.C., Houston, Chicago, Orlando, San Juan, Boston, David, Chiriquí, Dallas, San Francisco, San José, Austin, Seattle, Salt Lake City, Minneapolis, Atlanta, Detroit.

Travelers frequently search for route combinations, such as Santiago de los Caballeros and Fort Lauderdale, New York, San Juan, Atlanta, Boston, Norfolk, Chicago, Houston, Minneapolis, Philadelphia, Miami, Cleveland, Salt Lake City, Tampa, Reno, Mobile, Asheville, Seattle, Laredo, Syracuse.

Panama is mainly served by Tocumen International. But there are other airports nearby, including Albrook Marcos A. Gelabert International, Panamá Pacífico International Airport.

The main airport in Panama is Tocumen International. It is also served by Chitre Alonso Valderrama.

The main airport in Santiago de los Caballeros is Cibao International. It is also served by Las Américas International, Cap-Haïtien International, Cibao International, Gregorio Luperón International, La Isabela International, La Romana International, Samaná El Catey International.

Currently, you can fly between Panama and Santiago de los Caballeros with JetBlue Airways, Copa Airlines, Avianca, Spirit Airlines, Frontier Airlines.

If you don’t have specific dates for your trip between Panama and Santiago de los Caballeros, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Panama and Santiago de los Caballeros, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Panama. The main one is Tocumen International and other nearby airports include Chitre Alonso Valderrama