Cheap flights from Roanoke to Lexington from $278

Travelers frequently search for route combinations, such as Roanoke and Phoenix, Orlando, Detroit, Catania, Malé, Vancouver, Dubai, Freeport, Tokyo, Frankfurt, Charleston, Harrisburg, Tulsa, Antananarivo, Cancún, Kraków, Istanbul, Santo Domingo, Cebu, Antalya.

Travelers frequently search for route combinations, such as Lexington and Fort Lauderdale, Tampa, Orlando, Denver, Boston, Atlantic City, Dallas, Kalispell, Laredo, Greenville, Chicago, Grand Rapids, Raleigh, Concord, West Palm Beach, Kauai, Allentown, Grand Junction, St. Louis, Hartford.

The main airport in Roanoke is Roanoke–Blacksburg Regional. It is also served by Raleigh–Durham International, Charlotte Douglas International, Richmond International, Piedmont Triad International, Yeager, Concord Regional, Roanoke–Blacksburg Regional, Greenbrier Valley, Tri-Cities Regional, Shenandoah Valley Regional.

The main airport in Lexington is Blue Grass. It is also served by Cincinnati/Northern Kentucky International, Indianapolis International, Louisville International, Blue Grass, Rickenbacker International, Tri-State, Dayton International, Owensboro–Daviess County Regional.

Currently, you can fly between Roanoke and Lexington with United Airlines.

If you don’t have specific dates for your trip between Roanoke and Lexington, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Roanoke and Lexington, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Roanoke. The main one is Roanoke–Blacksburg Regional and other nearby airports include Raleigh–Durham International, Charlotte Douglas International, Richmond International, Piedmont Triad International, Yeager, Concord Regional, Roanoke–Blacksburg Regional, Greenbrier Valley, Tri-Cities Regional, Shenandoah Valley Regional

There are a number of airports in and around Lexington. The main one is Blue Grass and other nearby airports include Cincinnati/Northern Kentucky International, Indianapolis International, Louisville International, Blue Grass, Rickenbacker International, Tri-State, Dayton International, Owensboro–Daviess County Regional.