Cheap flights from San Diego to Santa Cruz de la Sierra from $354

Travelers frequently search for route combinations, such as San Diego and Las Vegas, New York, Dallas, Portland, Salt Lake City, Denver, Calgary, Atlanta, Seattle, San Francisco, Phoenix, Chicago, Reno, Washington, D.C., San Jose, Orlando, Honolulu, Minneapolis, Boston, Houston.

Travelers frequently search for route combinations, such as Santa Cruz de la Sierra and La Paz, Miami, Cochabamba, New York, Washington, D.C., Sucre, Los Angeles, Charlotte, Tarija, Uyuni, Santiago de Chile, Trinidad, Bogotá, Lima, Panama, Buenos Aires, Madrid, Rio de Janeiro, Guadalajara, Moline.

San Diego is mainly served by San Diego International. But there are other airports nearby, including McClellan–Palomar, Marine Corps Air Station Miramar.

The main airport in San Diego is San Diego International. It is also served by Los Angeles International, Tijuana International, John Wayne, Ontario International, Palm Springs International, Mexicali International, Hollywood Burbank, Long Beach, Imperial County, Hawthorne Municipal.

Currently, you can fly between San Diego and Santa Cruz de la Sierra with Avianca, Hawaiian Airlines, Copa Airlines, Boliviana de Aviación, LATAM Airlines.

If you don’t have specific dates for your trip between San Diego and Santa Cruz de la Sierra, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between San Diego and Santa Cruz de la Sierra, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around San Diego. The main one is San Diego International and other nearby airports include Los Angeles International, Tijuana International, John Wayne, Ontario International, Palm Springs International, Mexicali International, Hollywood Burbank, Long Beach, Imperial County, Hawthorne Municipal

This depends on the airline’s flight schedule. You can easily select your preferred departure time when you search on our website or mobile app. Choose the time of day you wish to depart from San Diego, such as morning, afternoon, evening, or night, or select the exact hours for departure.