Cheap flights from San Diego to St. Louis

Choose between United Airlines, American Airlines, or Frontier Airlines to find the best price

Why travel with Kiwi.com?
Best price

100+ million searches a day to find you the best available price.

Unique content

Explore unique options you won’t find anywhere else.

Travel hacks

Discover flight options and prices the airlines don’t want you to see.

Tips to know when travelling to St. Louis

St. Louis travel tips

1) Admire the mosaic ceiling of the Cathedral Basilica in St. Louis

The Cathedral Basilica of St. Louis is also known as the Cathedral of the Roman Catholic Church or St. Louis Cathedral. The temple, which was built in 1914, accommodates 2.5 thousand parishioners on benches and about 5 thousand people standing. The cathedral is famous for its mosaic ceiling, which took more than 70 years to create. It is composed of over forty million mosaic pieces. There is also a museum in the basement (admission is free).

2) Watch out for stormy weather in St. Louis

Be sure to check the weather forecast and storm warnings before visiting St. Louis. The most unpleasant thing about the climate of St. Louis is storms, which can be very severe (strong winds, showers, and tornadoes) and occur at any time of the year. According to statistics, St. Louis experiences stormy weather 48 days a year.

3) MetroBus in St. Louis covers many areas of the city but is time-consuming

Metro's bus system offers 70+ routes on both sides of the Mississippi River. Buses are the best option to get to such St. Louis regions as Tower Grove and The Hill. Still, remember that buses are time-consuming, so if you are in a hurry, you better use MetroLink or hail a taxi.

Travelers usually depart from San Diego International, San Diego, CA Bus Station, San Diego, CA - Old Town, San Diego, CA - Santa Fe, or San Diego, CA - La Jolla when they travel from San Diego to St. Louis. Book your trip to arrive at St. Louis Lambert International, or St. Louis Union Station. The most popular airlines for this route are United Airlines, American Airlines, Frontier Airlines, Delta Air Lines, and Spirit Airlines. San Diego and St. Louis have 254 direct flights per week.

Check-in for a flight from San Diego to St. Louis

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
United AirlinesUALUAYesNo
American AirlinesAALAAYesNo
Frontier AirlinesFFTF9NoOpens 24 days before flight
Closes 1 hours before flight
Delta Air LinesDALDLYesOpens 24 days before flight
Closes 1 hours before flight
Spirit AirlinesNKSNKNoOpens 24 days before flight
Closes 1 hours before flight

Frequently asked questions

What are the most popular routes to and from San Diego?
Travelers frequently search for route combinations, such as San Diego and Las Vegas, Denver, Austin, Cincinnati, Philadelphia, New York, Atlanta, Washington, D.C., Raleigh, Chicago, Phoenix, Orlando, San Antonio, Charlotte, Minneapolis, Detroit, Cleveland, New Orleans, Dallas, San Francisco.
What are the most popular routes to and from St. Louis?
Travelers frequently search for route combinations, such as St. Louis and Los Angeles, Denver, Las Vegas, Atlanta, San Francisco, Orlando, Minneapolis, Phoenix, Sacramento, Seattle, Houston, New York, Fort Lauderdale, Washington, D.C., Salt Lake City, San Jose, Oakland, Portland, Fresno, London.
Which airports are there in San Diego?
San Diego is mainly served by San Diego International. But there are other airports nearby, including McClellan–Palomar, Marine Corps Air Station Miramar.
What airports are near San Diego?
The main airport in San Diego is San Diego International. It is also served by Los Angeles International, Ontario International, Tijuana International, John Wayne, Hollywood Burbank, Mexicali International, Long Beach, Palm Springs International, Imperial County, Hawthorne Municipal.
What airports are near St. Louis?
The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, Central Illinois Regional, General Wayne A. Downing Peoria International, MidAmerica St. Louis, Evansville Regional, Williamson County Regional, Quincy Regional, Decatur, Abraham Lincoln Capital, Cape Girardeau Regional.
What buses and trains depart from San Diego?
A number of bus and train companies depart from San Diego, including Greyhound.
Is it possible to combine flights, buses, and trains in one itinerary when traveling between San Diego and St. Louis?
Yes, it's possible to combine different modes of transport between San Diego and St. Louis thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between San Diego and St. Louis can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.
What is Virtual Interlining and how do I use it?
Virtual Interlining provides a revolutionary way of traveling. You can combine different modes of transport like flights, trains, and buses into one itinerary. And this often saves money. Thanks to the world's largest carrier database, the Kiwi.com search function enables anyone to mix and match different modes of transport easily.
Which airlines fly between San Diego and St. Louis?
Currently, you can fly between San Diego and St. Louis with United Airlines, American Airlines, Frontier Airlines, Delta Air Lines, Spirit Airlines.
When's the best time to travel between San Diego and St. Louis?
What flights operate between San Diego and St. Louis?
How many airports are there near San Diego?
How many airports are there near St. Louis?
Is it possible to reach San Diego by bus or train?
What time do nonstop (direct) flights between San Diego and St. Louis depart?
What time do nonstop (direct) flights between San Diego and St. Louis arrive?
What time do flights between San Diego and St. Louis depart?
What time do flights between San Diego and St. Louis arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any A and any B in the world by plane, train, and bus. Find the cheapest routes and best deals for you, as well as the best dates on which to travel.

Explore alternative trips

Flights from San Diego

Flights to St. Louis

Popular routes

Find the best connection from San Diego to St. Louis

Search, compare, and book flights, trains, or buses to get there.

Search flights, trains & buses