Cheap flights from San Francisco to Palermo from $345

Travelers frequently search for route combinations, such as San Francisco and Calgary, New York, Las Vegas, Los Angeles, Phoenix, Dallas, Toronto, Barcelona, Chicago, Mexico City, San Diego, Vancouver, Denver, Seoul, Ontario, Tokyo, Minneapolis, Paris, Salt Lake City, Atlanta.

Travelers frequently search for route combinations, such as Palermo and New York, Los Angeles, Orlando, Boston, Washington, D.C., Pittsburgh, New Orleans, Miami, Seattle, Minneapolis, Dallas, Naples, Barcelona, Tunis, Paris, Rome, London, Prague, Milan, Ibiza.

The main airport in San Francisco is San Francisco International. It is also served by San Francisco International, Sacramento International, Oakland International, San Jose International, Stockton Metropolitan, Monterey Regional, Charles M. Schulz–Sonoma County, Merced Regional.

The main airport in Palermo is Falcone–Borsellino. It is also served by Catania–Fontanarossa, Falcone–Borsellino, Pantelleria, Vincenzo Florio Airport Trapani–Birgi, Comiso.

Currently, you can fly between San Francisco and Palermo with Ryanair, Hawaiian Airlines, Vueling, Norse Atlantic Airways, ITA Airways.

If you don’t have specific dates for your trip between San Francisco and Palermo, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between San Francisco and Palermo, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around San Francisco. The main one is San Francisco International and other nearby airports include San Francisco International, Sacramento International, Oakland International, San Jose International, Stockton Metropolitan, Monterey Regional, Charles M. Schulz–Sonoma County, Merced Regional

There are a number of airports in and around Palermo. The main one is Falcone–Borsellino and other nearby airports include Catania–Fontanarossa, Falcone–Borsellino, Pantelleria, Vincenzo Florio Airport Trapani–Birgi, Comiso.