Cheap flights from San Luis Obispo to San Antonio from $328

Travelers frequently search for route combinations, such as San Luis Obispo and Seattle, Puerto Vallarta, Portland, Denver, Spokane, Columbus, Palm Springs, Detroit, Omaha, Sylhet, Tijuana, Cúcuta, Tirana, Honolulu, Saint Thomas, Santa Cruz de la Sierra, Puerto Escondido, Oaxaca, Norfolk, Indianapolis, Madrid.

Travelers frequently search for route combinations, such as San Antonio and Mexico City, Orlando, Guadalajara, Las Vegas, San Diego, Los Angeles, New York, Atlanta, Seattle, Santiago de Querétaro, Philadelphia, San Francisco, Portland, Sacramento, Salt Lake City, Denver, Raleigh, London, Frankfurt, Phoenix.

The main airport in San Luis Obispo is San Luis Obispo County Regional. It is also served by Fresno Yosemite International, Hollywood Burbank, San Luis Obispo County Regional, Monterey Regional, Santa Barbara Municipal, Meadows Field, Santa Maria Public.

The main airport in San Antonio is San Antonio International. It is also served by Austin–Bergstrom International, San Antonio International, Piedras Negras International, Nuevo Laredo International, Laredo International, Victoria Regional, Corpus Christi International, Killeen–Fort Hood Regional, Easterwood.

Currently, you can fly between San Luis Obispo and San Antonio with Alaska Airlines.

If you don’t have specific dates for your trip between San Luis Obispo and San Antonio, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between San Luis Obispo and San Antonio, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around San Luis Obispo. The main one is San Luis Obispo County Regional and other nearby airports include Fresno Yosemite International, Hollywood Burbank, San Luis Obispo County Regional, Monterey Regional, Santa Barbara Municipal, Meadows Field, Santa Maria Public

There are a number of airports in and around San Antonio. The main one is San Antonio International and other nearby airports include Austin–Bergstrom International, San Antonio International, Piedras Negras International, Nuevo Laredo International, Laredo International, Victoria Regional, Corpus Christi International, Killeen–Fort Hood Regional, Easterwood.