Cheap flights from Santorini to Mytilene from $160

Travelers frequently search for route combinations, such as Santorini and New York, Orlando, Miami, Los Angeles, Washington, D.C., Boston, Houston, Athens, Dallas, Detroit, San Francisco, Las Vegas, Barcelona, Naples, Rome, Paris, Dubrovnik, Milan, Split, Istanbul.

Travelers frequently search for route combinations, such as Mytilene and Boston, New York, Tel Aviv, Amsterdam, Athens, Berlin, Tampa, Key West, Pensacola, Dharamshala, Zürich, Asheville, Málaga, Dublin, Cologne, Bucharest, Santa Ana, Edinburgh, Des Moines, Miami.

The main airport in Santorini is Santorini (Thira) National. It is also served by Santorini (Thira) National, Heraklion International, Chania International.

The main airport in Mytilene is Mytilene International. It is also served by Mytilene International, Chios Island National, Balıkesir Koca Seyit, Çanakkale.

Currently, you can fly between Santorini and Mytilene with Aegean, SKY express, Ryanair, Jet2, Wizz Air Malta.

If you don’t have specific dates for your trip between Santorini and Mytilene, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Santorini and Mytilene, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Santorini. The main one is Santorini (Thira) National and other nearby airports include Santorini (Thira) National, Heraklion International, Chania International

There are a number of airports in and around Mytilene. The main one is Mytilene International and other nearby airports include Mytilene International, Chios Island National, Balıkesir Koca Seyit, Çanakkale.