Cheap flights from St. Louis to Columbus from $135

Travelers frequently search for route combinations, such as St. Louis and Las Vegas, Cancún, Orlando, Los Angeles, San Francisco, Denver, Mexico City, Tuxtla Gutiérrez, Toronto, Ottawa, Lima, Buenos Aires, Cali, Sydney, Warsaw, San José, Washington, D.C., Reykjavik, Fort Lauderdale, Melbourne.

Travelers frequently search for route combinations, such as Columbus and New York, Orlando, Fort Lauderdale, Raleigh, Los Angeles, Tampa, Fort Myers, New Orleans, London, Paris, Dallas, Las Vegas, Mexico City, Sarasota, Seattle, Punta Gorda, Boston, Medellín, Hartford, Edmonton.

The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, General Wayne A. Downing Peoria International, Columbia Regional, Evansville Regional, MidAmerica St. Louis, Central Illinois Regional, Abraham Lincoln Capital, Cape Girardeau Regional, Waynesville-St. Robert Regional, Williamson County Regional.

The main airport in Columbus is John Glenn Columbus International. It is also served by Cincinnati/Northern Kentucky International, Cleveland Hopkins International, Pittsburgh International, Akron–Canton, Fort Wayne International, Dayton International, Yeager, Tri-State, Toledo Express, North Central West Virginia.

Currently, you can fly between St. Louis and Columbus with Frontier Airlines, United Airlines, Allegiant Air, Spirit Airlines, BREEZE.

If you don’t have specific dates for your trip between St. Louis and Columbus, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between St. Louis and Columbus, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around St. Louis. The main one is St. Louis Lambert International and other nearby airports include St. Louis Lambert International, General Wayne A. Downing Peoria International, Columbia Regional, Evansville Regional, MidAmerica St. Louis, Central Illinois Regional, Abraham Lincoln Capital, Cape Girardeau Regional, Waynesville-St. Robert Regional, Williamson County Regional

There are a number of airports in and around Columbus. The main one is John Glenn Columbus International and other nearby airports include Cincinnati/Northern Kentucky International, Cleveland Hopkins International, Pittsburgh International, Akron–Canton, Fort Wayne International, Dayton International, Yeager, Tri-State, Toledo Express, North Central West Virginia.