Cheap flights from St. Louis to Portsmouth from $136

Travelers frequently search for route combinations, such as St. Louis and Las Vegas, Cancún, Orlando, Los Angeles, San Francisco, Denver, Mexico City, Tuxtla Gutiérrez, Toronto, Ottawa, Lima, Buenos Aires, Cali, Sydney, Warsaw, San José, Washington, D.C., Reykjavik, Fort Lauderdale, Melbourne.

Travelers frequently search for route combinations, such as Portsmouth and Orlando, Punta Gorda, Oklahoma City, Fresno, Tampa, Detroit, Sarasota, Pittsburgh, San Diego, Reno, El Paso, San Jose, Los Angeles, Dallas, Salt Lake City, Phoenix, Jacksonville, Indianapolis, Asheville, Denver.

The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, Columbia Regional, General Wayne A. Downing Peoria International, Evansville Regional, MidAmerica St. Louis, Abraham Lincoln Capital, Waynesville-St. Robert Regional, Central Illinois Regional, Cape Girardeau Regional, Quincy Regional.

The main airport in Portsmouth is Portsmouth International Airport at Pease. It is also served by Logan International, Bradley International, Rhode Island T. F. Green Int'l Airport, Portland International Jetport, Manchester–Boston Regional, Bangor International, Portsmouth International Airport at Pease, Lebanon Municipal, Augusta State, Knox County Regional.

Currently, you can fly between St. Louis and Portsmouth with Frontier Airlines, BREEZE, Allegiant Air, Southern Airways Express, JetBlue Airways.

If you don’t have specific dates for your trip between St. Louis and Portsmouth, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between St. Louis and Portsmouth, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around St. Louis. The main one is St. Louis Lambert International and other nearby airports include St. Louis Lambert International, Columbia Regional, General Wayne A. Downing Peoria International, Evansville Regional, MidAmerica St. Louis, Abraham Lincoln Capital, Waynesville-St. Robert Regional, Central Illinois Regional, Cape Girardeau Regional, Quincy Regional

There are a number of airports in and around Portsmouth. The main one is Portsmouth International Airport at Pease and other nearby airports include Logan International, Bradley International, Rhode Island T. F. Green Int'l Airport, Portland International Jetport, Manchester–Boston Regional, Bangor International, Portsmouth International Airport at Pease, Lebanon Municipal, Augusta State, Knox County Regional.