Cheap flights from Tupelo to Key West from $178

Travelers frequently search for route combinations, such as Tupelo and Nashville, Little Rock, Lucknow, Buffalo, Miami, Chicago, Brasília, Louisville, Columbus, Sacramento, Charleston, Memphis, Manila, Dubai, Dublin, Oslo, Accra, Boise, Honolulu, Boston.

Travelers frequently search for route combinations, such as Key West and Tampa, Orlando, Tallahassee, Pensacola, Fort Lauderdale, Providence, Albany, Milwaukee, Detroit, Fort Myers, Spokane, Raleigh, Owensboro, Portsmouth, Albuquerque, Cleveland, Plattsburgh, West Palm Beach, Atlanta, Flint.

The main airport in Tupelo is Tupelo Regional. It is also served by Memphis International, Huntsville International, Birmingham-Shuttlesworth International, Tupelo Regional, Jonesboro Municipal, Northwest Alabama Regional, McKellar–Sipes Regional, Meridian Regional, Golden Triangle Regional.

The main airport in Key West is Key West International. It is also served by Miami International, Key West International.

Currently, you can fly between Tupelo and Key West with Frontier Airlines, BREEZE, Allegiant Air, JetBlue Airways.

If you don’t have specific dates for your trip between Tupelo and Key West, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Tupelo and Key West, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Tupelo. The main one is Tupelo Regional and other nearby airports include Memphis International, Huntsville International, Birmingham-Shuttlesworth International, Tupelo Regional, Jonesboro Municipal, Northwest Alabama Regional, McKellar–Sipes Regional, Meridian Regional, Golden Triangle Regional

There are a number of airports in and around Key West. The main one is Key West International and other nearby airports include Miami International, Key West International.