Cheap flights from Cape Town to Santa Cruz de la Sierra from £473

Travelers frequently search for route combinations, such as Cape Town and London, Johannesburg, Durban, São Paulo, Harare, Maputo, Belfast, Birmingham, Manchester, Nairobi, Victoria Falls, Windhoek, East London, Mount Kilimanjaro, Port Elizabeth, Buenos Aires, Kimberley, Northern Cape, Hoedspruit, Limpopo, Gaborone, Mauritius Island.

Travelers frequently search for route combinations, such as Santa Cruz de la Sierra and La Paz, London, Sucre, Cochabamba, Uyuni, Edinburgh, Bogotá, Tarija, Madrid, São Paulo, Miami, Johannesburg, Dublin, Lima, Trinidad, Santiago de Chile, Cusco, Rio de Janeiro, Berlin, Medellín.

The main airport in Cape Town is Cape Town International. It is also served by Cape Town International.

Currently, you can fly between Cape Town and Santa Cruz de la Sierra with Boliviana de Aviación, Fly Safair, LATAM Airlines, Gol Transportes Aéreos, South African Airways.

If you don’t have specific dates for your trip between Cape Town and Santa Cruz de la Sierra, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Cape Town and Santa Cruz de la Sierra, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Cape Town. The main one is Cape Town International and other nearby airports include Cape Town International

This depends on the airline’s flight schedule. You can easily select your preferred departure time when you search on our website or mobile app. Choose the time of day you wish to depart from Cape Town, such as morning, afternoon, evening, or night, or select the exact hours for departure.

This depends on the airline’s flight schedule. You can easily select your preferred arrival time when you search on our website or mobile app. Choose the time of day you wish to arrive at Santa Cruz de la Sierra, such as morning, afternoon, evening, or night, or select the exact hours for arrival.