La Serena to Santiago de Chile flights from £21

Flights starting at £21. Choose between LATAM Airlines, Sky Airline, or JetSMART to find the best price.

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Tips to know when travelling to Santiago de Chile

The distance between La Serena and Santiago de Chile is 388 km. The most popular airlines for this route are LATAM Airlines, Sky Airline, and JetSMART. La Serena and Santiago de Chile have 55 direct flights per week.

Weekly direct flights

MondaysTuesdaysWednesdaysThursdaysFridaysSaturdaysSundays
Direct flights8677686
Fly direct with

Sky Airline on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays, Saturdays, and Sundays.

JetSMART on Mondays, Wednesdays, Fridays, and Sundays.

LATAM Airlines on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays, Saturdays, and Sundays.

Check-in for a flight from La Serena to Santiago de Chile

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
LATAM AirlinesLANLAYesNo
Sky AirlineSKUH2YesNo
JetSMARTJATJAYesOpens 72 days before flight
Closes 1 hours before flight
Learn more about COVID-19 restrictions in Chile in our dedicated Stories article.

Frequently asked questions

How long does it take to travel from La Serena to Santiago de Chile?
A one-way nonstop (direct) flight between La Serena and Santiago de Chile takes around 0.91 hours.
What is the flight distance between La Serena and Santiago de Chile?
The flight distance between La Serena and Santiago de Chile is 388 km.
What airlines offer nonstop (direct) flights between La Serena and Santiago de Chile?
Several carriers operate flights between La Serena and Santiago de Chile. Airlines offering nonstop (direct) flights include LATAM Airlines, Sky Airline, JetSMART.
What are the most popular routes to and from La Serena?
Travelers frequently search for route combinations, such as La Serena and Calama, Valdivia, Taipei, Cusco, Buenos Aires, Iquique, La Paz, Puerto Montt, Antofagasta, Arequipa, Temuco, Barranquilla, Lima, New York, Orlando, Las Vegas, Denver, Chicago, Miami, Los Angeles.
What are the most popular routes to and from Santiago de Chile?
Travelers frequently search for route combinations, such as Santiago de Chile and London, Cusco, Buenos Aires, Lima, Caracas, Calama, Sydney, Bogotá, Cúcuta, Montreal, Dublin, Punta Arenas, Mendoza, Toronto, Rio de Janeiro, Auckland, São Paulo, Bangkok, Arequipa, Puerto Natales.
What airports are near La Serena?
The main airport in La Serena is La Florida. It is also served by La Florida.
What airports are near Santiago de Chile?
The main airport in Santiago de Chile is Comodoro Arturo Merino Benítez International. It is also served by Comodoro Arturo Merino Benítez International.
Is it possible to combine flights, buses, and trains in one itinerary when traveling between La Serena and Santiago de Chile?
Yes, it's possible to combine different modes of transport between La Serena and Santiago de Chile thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between La Serena and Santiago de Chile can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.
What is Virtual Interlining and how do I use it?
Virtual Interlining provides a revolutionary way of traveling. You can combine different modes of transport like flights, trains, and buses into one itinerary. And this often saves money. Thanks to the world's largest carrier database, the Kiwi.com search function enables anyone to mix and match different modes of transport easily.
Which airlines fly between La Serena and Santiago de Chile?
When's the best time to travel between La Serena and Santiago de Chile?
What flights operate between La Serena and Santiago de Chile?
How many airports are there near La Serena?
How many airports are there near Santiago de Chile?
What time do nonstop (direct) flights between La Serena and Santiago de Chile depart?
What time do nonstop (direct) flights between La Serena and Santiago de Chile arrive?
What time do flights between La Serena and Santiago de Chile depart?
What time do flights between La Serena and Santiago de Chile arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any A and any B in the world by plane, train, and bus. Find the cheapest routes and best deals for you, as well as the best dates on which to travel.

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