Cheap flights from Mexico City, Mexico to Panama City, Panama

Flights starting at £129. Choose between Copa Airlines, Avianca, or AeroMéxico to find the best price.

Make your travel wishlist, we'll do the rest
Hidden deals
Effortless booking
Travel hacking
Travelers usually depart from Mexico City International, Felipe Ángeles International Airport, Mexico City - Norte, Mexico City - Oriente San Lázaro, or Mexico City - Ignacio Zaragoza when they travel from Mexico City to Panama. Book your trip to arrive at Tocumen International, Panamá Pacífico International Airport, or Albrook Marcos A. Gelabert International. The distance between Mexico City and Panama is 2424 km. The most popular airlines for this route are Copa Airlines, Avianca, AeroMéxico, Volaris, and VivaAerobus. Mexico City and Panama have 401 direct flights per week.

Weekly direct flights

Discover the top airlines offering direct flights from Mexico City to Panama in the next month. You’ll find the number of daily direct flights per airline in the table.

Weekly direct flights for Mon 19.02 - Sun 25.02

AirlineMon 19.02Tue 20.02Wed 21.02Thu 22.02Fri 23.02Sat 24.02Sun 25.02
---346451

Weekly direct flights for Mon 26.02 - Sun 03.03

AirlineMon 26.02Tue 27.02Wed 28.02Thu 29.02Fri 01.03Sat 02.03Sun 03.03
54439118

Weekly direct flights for Mon 04.03 - Sun 10.03

AirlineMon 04.03Tue 05.03Wed 06.03Thu 07.03Fri 08.03Sat 09.03Sun 10.03
11698476

Weekly direct flights for Mon 11.03 - Sun 17.03

AirlineMon 11.03Tue 12.03Wed 13.03Thu 14.03Fri 15.03Sat 16.03Sun 17.03
79979119

Check-in for a flight from Mexico City to Panama

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
Copa AirlinesCMPCMYes0
0
AviancaAVAAVNoOpens 48 days before flight
Closes 1 hours before flight
AeroMéxicoAMXAMYes0
0
VolarisVOIY4NoOpens 24 days before flight
Closes 1 hours before flight
VivaAerobusVIVVBNoOpens 72 days before flight
Closes 4 hours before flight

Weather in Panama

Average Weather

MonthAverage monthly max temperatureAverage monthly min temperature
January28°C23°C
February29°C23°C
March29°C24°C
April30°C24°C
May29°C25°C
June29°C25°C
July29°C24°C
August28°C24°C
September28°C24°C
October28°C24°C
November27°C24°C
December28°C23°C
Hottest Month
30°C
April
Coldest month
23°C
January
Sunny days
143
days per year

14 day forecast

Sunday
18 Feb
32°C25°C
25 Feb
32°C24°C
Monday
19 Feb
85%
33°C25°C
26 Feb
31°C24°C
Tuesday
20 Feb
32°C24°C
27 Feb
31°C24°C
Wednesday
21 Feb
84%
32°C23°C
28 Feb
32°C24°C
Thursday
22 Feb
89%
29°C23°C
29 Feb
33°C24°C
Friday
23 Feb
72%
30°C22°C
1 Mar
30°C24°C
Saturday
24 Feb
30°C22°C
2 Mar
87%
32°C24°C

Frequently asked questions

How long does it take to travel from Mexico City to Panama?
What is the flight distance between Mexico City and Panama?
What airlines offer nonstop (direct) flights between Mexico City and Panama?
What are the most popular routes to and from Mexico City?
What are the most popular routes to and from Panama?
What airports are near Mexico City?
What airports are near Panama?
What buses and trains depart from Mexico City?
Is it possible to combine flights, buses, and trains in one itinerary when traveling between Mexico City and Panama?
What is Virtual Interlining and how do I use it?
Which airlines fly between Mexico City and Panama?
When's the best time to travel between Mexico City and Panama?
What flights operate between Mexico City and Panama?
How many airports are there near Mexico City?
How many airports are there near Panama?
Is it possible to reach Mexico City by bus or train?
What time do nonstop (direct) flights between Mexico City and Panama depart?
What time do nonstop (direct) flights between Mexico City and Panama arrive?
What time do flights between Mexico City and Panama depart?
What time do flights between Mexico City and Panama arrive?

Explore alternative trips

Flights from Mexico City

Flights to Panama

Popular routes

Find the best connection from Mexico City to Panama
Search flights, trains & buses
We hack the system,
you fly for less