£274 Cheap flights from Mexico City to Panama City

Today’s cheapest flight deals to Panama City

Updated many times a day, so prices are always up to date. Found one? Book it now.

How do we find these prices? Every 2 hours, we check Kiwi.com for the cheapest price for each trip. Prices can change and may not be available on every flight or date.

Key info about flying to Panama

Depart from

Mexico City International

Arrive to

Tocumen International

Flights per week

400

Flight distance

2413 km

Worth visiting

Panama Canal

Explore flight deals to Panama City

Direct
Mon, Dec 7
Mexico City MEXPanama PTY

£145
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Direct
Mon, Dec 7
Mexico City MEXPanama PTY

£158
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Direct
Mon, Dec 7
Mexico City MEXPanama PTY

£159
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Direct
Fri, Nov 27
Mexico City MEXPanama PTY

£214
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1 stop
Sat, Nov 28
Mexico City MEXPanama PTY

£377
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Direct
Mon, Dec 7 – Thu, Dec 10
Mexico City MEXPanama PTY

£274
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Direct
Mon, Dec 7 – Wed, Dec 9
Mexico City MEXPanama PTY

£289
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Direct
Mon, Dec 7 – Wed, Dec 9
Mexico City MEXPanama PTY

£290
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Direct
Mon, Dec 7 – Wed, Dec 9
Mexico City MEXPanama PTY

£291
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Ways to fly from Mexico City to Panama

Useful info to find a cheap flight from Mexico City to Panama and book your next trip.

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Direct flights from Mexico City to Panama

See how many direct flights run each week and which airlines operate them.

1Direct flights per week
0.14Daily average
SundayBusiest day

Airlines that fly from Mexico City to Panama

Options may vary by recent bookings and your search.

Getting from Panama City's airport to the city center

Panama City is served by Tocumen International Airport (PTY), the main international gateway located 24 km northeast of the city center. The airport offers various airport transfers to city center destinations including taxis, ride-hailing services, public buses, and the Metro connection via Corredor Sur. Journey times typically range from 30 minutes to over an hour depending on traffic conditions, which can be significant during peak hours. A smaller domestic airport, Marcos A. Gelabert International Airport (PAC), also known as Albrook Airport, is located just 3 km from downtown within the city limits.

How to get from Tocumen International Airport (PTY) to Panama City?

How to get from Marcos A. Gelabert International Airport (PAC) to Panama City?

Notes:

  • Prices in USD; table created in 2025 and subject to change.
  • Traffic in Panama City can be heavy, especially during rush hours (7-9 AM and 5-8 PM). Allow extra time.
  • The Metro requires a rechargeable Metro card, available at stations. Cash is not accepted on Metro or Metrobus.
  • Official airport taxis have fixed rates displayed at the taxi stand. Negotiate before boarding unofficial taxis.
  • Uber operates legally in Panama and picks up from designated areas at Tocumen Airport.
  • We recommend checking official transport websites for your travel planning.

Updated: December 2025

Weather in Panama

Average Weather

MonthAverage monthly max temperatureAverage monthly min temperature
January28°C23°C
February29°C23°C
March30°C23°C
April30°C24°C
May29°C25°C
June29°C25°C
July29°C24°C
August29°C24°C
September28°C24°C
October28°C24°C
November27°C23°C
December28°C23°C
Hottest Month
30°C
April
Coldest month
23°C
January
Sunny days
159
days per year

14 day forecast

Saturday
7 Nov
89%
28°C25°C
14 Nov
89%
29°C25°C
Sunday
8 Nov
78%
28°C25°C
15 Nov
90%
29°C25°C
Monday
9 Nov
71%
31°C24°C
16 Nov
91%
27°C25°C
Tuesday
10 Nov
80%
31°C25°C
17 Nov
86%
28°C24°C
Wednesday
11 Nov
87%
30°C24°C
18 Nov
86%
27°C25°C
Thursday
12 Nov
85%
29°C25°C
19 Nov
82%
30°C25°C
Friday
13 Nov
80%
28°C25°C
20 Nov
78%
30°C25°C
Travelers usually depart from Mexico City International, or Felipe Ángeles International Airport when they travel from Mexico City to Panama. Book your trip to arrive at Tocumen International, Albrook Marcos A. Gelabert International, or Panamá Pacífico International Airport. The distance between Mexico City and Panama is 2413 km. The most popular airlines for this route are Copa Airlines, Volaris, VivaAerobus, Avianca, and Wingo airlines. Mexico City and Panama have 400 direct flights per week.

Frequently asked questions

How long does it take to travel from Mexico City to Panama?

What is the flight distance between Mexico City and Panama?

What airlines offer nonstop (direct) flights between Mexico City and Panama?

What are the most popular routes to and from Mexico City?

What are the most popular routes to and from Panama?

What airports are near Mexico City?

Which airlines fly between Mexico City and Panama?

When’s the best time to travel between Mexico City and Panama?

What flights operate between Mexico City and Panama?

How many airports are there near Mexico City?

What time do nonstop (direct) flights between Mexico City and Panama depart?

What time do nonstop (direct) flights between Mexico City and Panama arrive?

What time do flights between Mexico City and Panama depart?

What time do flights between Mexico City and Panama arrive?

The nearest countries with flights to Panama

Here is a list of countries people are flying from

Other destination countries from Mexico City

Here is a list of countries people are flying to

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