Cheap flights from Panama City to Brussels from £550

Cheap flights from Panama City to Brussels from £550

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1 stop
Thu, Jul 23
Panama PTYBrussels BRU
£550
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1 stop
Sat, Jul 25
Panama PTYBrussels BRU
£550
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1 stop
Mon, Jul 20
Panama PTYBrussels BRU
£550
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1 stop
Tue, Jul 21
Panama PTYBrussels BRU
£550
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1 stop
Fri, Jul 24
Panama PTYBrussels BRU
£550
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1 stop
Wed, Jul 22
Panama PTYBrussels BRU
£550
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1 stop
Mon, Jul 20 – Fri, Jul 24
Panama PTYBrussels BRU
£1,055
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1 stop
Mon, Jul 20 – Fri, Jul 24
Panama PTYBrussels BRU
£1,180
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1 stop
Thu, Jul 23 – Tue, Jul 28
Panama PTYBrussels BRU
£1,183
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1 stop
Mon, Jul 20 – Sat, Jul 25
Panama PTYBrussels BRU
£1,183
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1 stop
Fri, Jul 24 – Wed, Jul 29
Panama PTYBrussels BRU
£1,183
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1 stop
Thu, Jul 23 – Mon, Jul 27
Panama PTYBrussels BRU
£1,183
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How much do flights to Brussels cost?

Cheapest one-way trip

£550

Cheapest round-trip

£1,055

Average round-trip

£1,183

Most popular airline

Avianca

Getting from Brussels airport to the city center

Fastest option: Airport Express train. Best value: STIB bus lines and regional trains.

Brussels is served by Brussels Airport (BRU), located 12 km northeast of the city center. A variety of airport transfers to city center destinations are available, including direct trains, buses, taxis, ride-hailing services, and private transfers. The Airport Express train offers the quickest connection to Brussels-Central, Brussels-Midi, and Brussels-Nord stations. Budget travelers can opt for STIB bus lines or regional trains. Journey times and costs vary depending on your final destination and traffic conditions.

Transport Option

Typical time

Typical cost

Frequency

Best for

17-21 min

€12 – €14; standard single fare

every 10–15 min (traffic dependent)

fastest to city center

30-45 min

€3 – €4; STIB single ticket

every 20–30 min (traffic dependent)

budget travelers

25-40 min

€3 – €4; STIB single ticket

every 20–30 min (traffic dependent)

north Brussels destinations

20-45 min

€45 – €55; metered; varies by traffic

on-demand 24/7 (traffic dependent)

door-to-door convenience

20-45 min

€30 – €50; varies with demand

on-demand 24/7 (traffic dependent)

app-based booking

20-40 min

€60 – €90; pre-booked fixed rate

pre-booked (traffic dependent)

groups or business travel

20-45 min

€35 – €80; per day; varies by provider

on-demand (traffic dependent)

flexibility and onward travel

Notes:

  • Prices in EUR; table created in 2025 and subject to change.
  • The Airport Express train departs from the airport's underground station (Level -1).
  • STIB tickets can be purchased at the airport or via the STIB-MIVB app.
  • Taxi fares are metered; ride-hailing prices vary with demand. Road traffic can significantly affect journey times.
  • We recommend checking official transport websites for your travel planning.

Updated: December 2025

Key info about flying to Brussels

Depart from
Tocumen International
Arrive to
Brussels
Average flights per week
400
Flight distance
Worth visiting
Andaz Amsterdam Prinsengracht - Anne Frank Huis - IJsselmonde - La Grand-Place, Brussels - Rijksmuseum - Van Gogh Museum - Voorne-Putten - Windmill Complex at Kinderdijk

Check-in for a flight from Panama to Brussels

NameCarrier codeIATA CodePassport needed during booking
AviancaAVAAVNo
RyanairRYRFRNo
Copa AirlinesCMPCMYes
Air EuropaAEAUXNo
World2fly 2WYes

Online check-in is not available for these airlines.

Weather in Brussels

Average Weather

MonthAverage monthly max temperatureAverage monthly min temperature
January5°C1°C
February7°C2°C
March11°C3°C
April14°C5°C
May17°C8°C
June21°C12°C
July23°C14°C
August23°C14°C
September20°C11°C
October15°C8°C
November10°C5°C
December6°C2°C
Hottest Month
23°C
August
Coldest month
1°C
January
Sunny days
266
days per year
Snow days
5
days per year

14 day forecast

Sunday
12 Jul
32°C18°C
19 Jul
36%
33°C20°C
Monday
13 Jul
30°C15°C
20 Jul
36%
35°C18°C
Tuesday
14 Jul
34°C18°C
21 Jul
33°C19°C
Wednesday
15 Jul
34°C19°C
22 Jul
34°C18°C
Thursday
16 Jul
33°C19°C
23 Jul
35°C21°C
Friday
17 Jul
36%
35°C20°C
24 Jul
35°C20°C
Saturday
18 Jul
34°C19°C
25 Jul
37°C19°C
Travelers usually depart from Tocumen International, Albrook Marcos A. Gelabert International, or Panamá Pacífico International Airport when they travel from Panama to Brussels. Book your trip to arrive at Brussels, Brussels South Charleroi, or Antwerp International. The most popular airlines for this route are Avianca, Ryanair, Copa Airlines, Air Europa, and World2fly. Panama and Brussels have 400 direct flights per week. When you arrive at Brussels, consider visiting Andaz Amsterdam Prinsengracht, Anne Frank Huis, IJsselmonde, La Grand-Place, Brussels, Rijksmuseum, Van Gogh Museum, Voorne-Putten, and Windmill Complex at Kinderdijk.

Frequently asked questions

What are the most popular routes to and from Panama?
Travelers frequently search for route combinations, such as Panama and Bocas Town, Bocas del Toro, Medellín, David, Chiriquí, Cartagena, Bogotá, San José, London, Managua, Cancún, Cali, Chitré, Caracas, Mexico City, Guatemala City, Puerto Vallarta, New York, Belize City, Lima, Barranquilla, Rio de Janeiro.
What are the most popular routes to and from Brussels?
Travelers frequently search for route combinations, such as Brussels and London, Manchester, Edinburgh, Bucharest, Tirana, Budapest, Warsaw, Sofia, Chișinău, Tel Aviv, Barcelona, Athens, Prague, Lisbon, Birmingham, Cluj-Napoca, Istanbul, Madrid, Vienna, Vilnius.
Which airports are there in Panama?
Panama is mainly served by Tocumen International. But there are other airports nearby, including Albrook Marcos A. Gelabert International, Panamá Pacífico International Airport.
What airports are near Panama?
The main airport in Panama is Tocumen International. It is also served by Chitre Alonso Valderrama.
What airports are near Brussels?
The main airport in Brussels is Brussels. It is also served by Charles de Gaulle Airport, Amsterdam Airport Schiphol, Beauvais–Tillé, Düsseldorf International Airport, Cologne Bonn Airport, Eindhoven, Frankfurt–Hahn, Luxembourg, Dortmund, Weeze.
Which airlines fly between Panama and Brussels?
Currently, you can fly between Panama and Brussels with Avianca, Ryanair, Copa Airlines, Air Europa, World2fly.
When’s the best time to travel between Panama and Brussels?
If you don’t have specific dates for your trip between Panama and Brussels, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.
What flights operate between Panama and Brussels?
Traveling between Panama and Brussels, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.
How many airports are there near Panama?
There are a number of airports in and around Panama. The main one is Tocumen International and other nearby airports include Chitre Alonso Valderrama
How many airports are there near Brussels?
What time do nonstop (direct) flights between Panama and Brussels depart?
What time do nonstop (direct) flights between Panama and Brussels arrive?
What time do flights between Panama and Brussels depart?
What time do flights between Panama and Brussels arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any origin and destination in the world by plane. Find the cheapest routes and best deals, as well as the best dates to travel.

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