Cheap flights from Santiago de los Caballeros to Brussels from £532

Cheap flights from Santiago de los Caballeros to Brussels from £532

Trusted by millions

Kiwi.com Guarantee for stress-free travel

One search, all the best deals

Explore flight deals to Brussels

2 stops
Wed, Aug 12
Santiago de los Caballeros STIBrussels CRL
£532
Search
2 stops
Wed, Aug 12
Santiago de los Caballeros STIBrussels BRU
£544
Search
2 stops
Sat, Aug 8
Santiago de los Caballeros STIBrussels CRL
£558
Search
2 stops
Thu, Aug 13
Santiago de los Caballeros STIBrussels CRL
£560
Search
2 stops
Thu, Aug 13
Santiago de los Caballeros STIBrussels BRU
£578
Search
1 stop
Sat, Aug 8
Santiago de los Caballeros STIBrussels CRL
£626
Search

Not happy with the results? Try some of our useful filters

Search by stops

Search by carrier

Search by price

Search by departure date

2 stops
Wed, Aug 12 – Sat, Aug 15
Santiago de los Caballeros STIBrussels CRL
£972
Search
3 stops
Tue, Aug 11 – Sat, Aug 15
Santiago de los Caballeros STIBrussels CRL
£976
Search
3 stops
Tue, Aug 11 – Sat, Aug 15
Santiago de los Caballeros STIBrussels CRL
£1,002
Search
3 stops
Tue, Aug 11 – Sat, Aug 15
Santiago de los Caballeros STIBrussels CRL
£1,003
Search
2 stops
Tue, Aug 11 – Sat, Aug 15
Santiago de los Caballeros STIBrussels BRU
£1,013
Search
1 stop
Wed, Aug 12 – Sat, Aug 15
Santiago de los Caballeros STIBrussels BRU
£1,092
Search

Not happy with the results? Try some of our useful filters

Search by stops

Search by carrier

Search by price

Search by departure date

How much do flights to Brussels cost?

Cheapest one-way trip

£532

Cheapest round-trip

£972

Average round-trip

£1,165

Includes rare itinerary

Travel hack

Most popular airline

JetBlue Airways

Getting from Brussels airport to the city center

Fastest option: Airport Express train. Best value: STIB bus lines and regional trains.

Brussels is served by Brussels Airport (BRU), located 12 km northeast of the city center. A variety of airport transfers to city center destinations are available, including direct trains, buses, taxis, ride-hailing services, and private transfers. The Airport Express train offers the quickest connection to Brussels-Central, Brussels-Midi, and Brussels-Nord stations. Budget travelers can opt for STIB bus lines or regional trains. Journey times and costs vary depending on your final destination and traffic conditions.

Transport Option

Typical time

Typical cost

Frequency

Best for

17-21 min

€12 – €14; standard single fare

every 10–15 min (traffic dependent)

fastest to city center

30-45 min

€3 – €4; STIB single ticket

every 20–30 min (traffic dependent)

budget travelers

25-40 min

€3 – €4; STIB single ticket

every 20–30 min (traffic dependent)

north Brussels destinations

20-45 min

€45 – €55; metered; varies by traffic

on-demand 24/7 (traffic dependent)

door-to-door convenience

20-45 min

€30 – €50; varies with demand

on-demand 24/7 (traffic dependent)

app-based booking

20-40 min

€60 – €90; pre-booked fixed rate

pre-booked (traffic dependent)

groups or business travel

20-45 min

€35 – €80; per day; varies by provider

on-demand (traffic dependent)

flexibility and onward travel

Notes:

  • Prices in EUR; table created in 2025 and subject to change.
  • The Airport Express train departs from the airport's underground station (Level -1).
  • STIB tickets can be purchased at the airport or via the STIB-MIVB app.
  • Taxi fares are metered; ride-hailing prices vary with demand. Road traffic can significantly affect journey times.
  • We recommend checking official transport websites for your travel planning.

Updated: December 2025

Key info about flying to Brussels

Depart from
Cibao International
Arrive to
Brussels
Average flights per week
400
Flight distance
Worth visiting
Andaz Amsterdam Prinsengracht - Anne Frank Huis - IJsselmonde - La Grand-Place, Brussels - Rijksmuseum - Van Gogh Museum - Voorne-Putten - Windmill Complex at Kinderdijk

Check-in for a flight from Santiago de los Caballeros to Brussels

NameCarrier codeIATA CodePassport needed during booking
JetBlue AirwaysJBUB6No
RyanairRYRFRNo
Brussels AirlinesBELSNNo
Air EuropaAEAUXNo
Iberia AirlinesIBEIBYes

Online check-in is not available for these airlines.

Weather in Brussels

Average Weather

MonthAverage monthly max temperatureAverage monthly min temperature
January5°C1°C
February7°C2°C
March11°C3°C
April14°C5°C
May17°C8°C
June21°C12°C
July23°C14°C
August23°C14°C
September20°C11°C
October15°C8°C
November10°C5°C
December6°C2°C
Hottest Month
23°C
August
Coldest month
1°C
January
Sunny days
266
days per year
Snow days
5
days per year

14 day forecast

Sunday
19 Jul
36%
21°C12°C
26 Jul
78%
20°C17°C
Monday
20 Jul
23°C11°C
27 Jul
27°C16°C
Tuesday
21 Jul
25°C10°C
28 Jul
17%
22°C13°C
Wednesday
22 Jul
24°C11°C
29 Jul
30°C12°C
Thursday
23 Jul
23°C13°C
30 Jul
31°C15°C
Friday
24 Jul
29°C11°C
31 Jul
29°C14°C
Saturday
25 Jul
17%
24°C16°C
1 Aug
31°C16°C
Book your trip to arrive at Brussels, Brussels South Charleroi, or Antwerp International. The most popular airlines for this route are JetBlue Airways, Ryanair, Brussels Airlines, Air Europa, and Iberia Airlines. Santiago de los Caballeros and Brussels have 400 direct flights per week. When you arrive at Brussels, consider visiting Andaz Amsterdam Prinsengracht, Anne Frank Huis, IJsselmonde, La Grand-Place, Brussels, Rijksmuseum, Van Gogh Museum, Voorne-Putten, and Windmill Complex at Kinderdijk.

Frequently asked questions

What are the most popular routes to and from Santiago de los Caballeros?
Travelers frequently search for route combinations, such as Santiago de los Caballeros and London, New York, San Juan, Fort Lauderdale, Orlando, Miami, Chicago, Washington, D.C., Atlanta, New Orleans, Panama, Tampa, Houston, Berlin, Austin, Hartford, Las Vegas, Medellín, Tortola, Mexico City.
What are the most popular routes to and from Brussels?
Travelers frequently search for route combinations, such as Brussels and London, Manchester, Edinburgh, Bucharest, Tirana, Budapest, Warsaw, Sofia, Chișinău, Tel Aviv, Barcelona, Athens, Prague, Lisbon, Birmingham, Cluj-Napoca, Istanbul, Madrid, Vienna, Vilnius.
What airports are near Santiago de los Caballeros?
The main airport in Santiago de los Caballeros is Cibao International. It is also served by Las Américas International, Cap-Haïtien International, Cibao International, La Isabela International, Gregorio Luperón International, La Romana International, Samaná El Catey International.
What airports are near Brussels?
The main airport in Brussels is Brussels. It is also served by Charles de Gaulle Airport, Amsterdam Airport Schiphol, Beauvais–Tillé, Düsseldorf International Airport, Cologne Bonn Airport, Frankfurt–Hahn, Eindhoven, Luxembourg, Dortmund, Weeze.
Which airlines fly between Santiago de los Caballeros and Brussels?
Currently, you can fly between Santiago de los Caballeros and Brussels with JetBlue Airways, Ryanair, Brussels Airlines, Air Europa, Iberia Airlines.
When’s the best time to travel between Santiago de los Caballeros and Brussels?
If you don’t have specific dates for your trip between Santiago de los Caballeros and Brussels, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.
What flights operate between Santiago de los Caballeros and Brussels?
Traveling between Santiago de los Caballeros and Brussels, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.
How many airports are there near Santiago de los Caballeros?
There are a number of airports in and around Santiago de los Caballeros. The main one is Cibao International and other nearby airports include Las Américas International, Cap-Haïtien International, Cibao International, La Isabela International, Gregorio Luperón International, La Romana International, Samaná El Catey International
How many airports are there near Brussels?
There are a number of airports in and around Brussels. The main one is Brussels and other nearby airports include Charles de Gaulle Airport, Amsterdam Airport Schiphol, Beauvais–Tillé, Düsseldorf International Airport, Cologne Bonn Airport, Frankfurt–Hahn, Eindhoven, Luxembourg, Dortmund, Weeze.
What time do nonstop (direct) flights between Santiago de los Caballeros and Brussels depart?
What time do nonstop (direct) flights between Santiago de los Caballeros and Brussels arrive?
What time do flights between Santiago de los Caballeros and Brussels depart?
What time do flights between Santiago de los Caballeros and Brussels arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any origin and destination in the world by plane. Find the cheapest routes and best deals, as well as the best dates to travel.

Search flightsSearch direct flights

Explore alternative trips

Flights from Santiago de los Caballeros

Flights to Brussels

Popular routes

The nearest countries with flights to Brussels

Here is a list of countries people are flying from

Other destination countries from Santiago de los Caballeros

Here is a list of countries people are flying to

Airports near Brussels

Download our app

Start your next adventure now. Download our app and explore cheap flights effortlessly!

Search flights
Find the best connection from Santiago de los Caballeros to Brussels

Search, compare, and book flights to get there.

Search flights