Cheap flights from Chicago to Knoxville

Flights starting at $75. Choose between American Airlines, United Airlines, or Delta Air Lines to find the best price.

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Travelers usually depart from O Hare International, Chicago Midway International, Chicago, IL - Union Station, Chicago Rockford International, or Chicago Downtown Greyhound Station when they travel from Chicago to Knoxville. Book your trip to arrive at McGhee Tyson, or Knoxville, TN - Greyhound Station. The distance between Chicago and Knoxville is 740 km. The most popular airlines for this route are American Airlines, United Airlines, Delta Air Lines, Allegiant Air, and Spirit Airlines. Chicago and Knoxville have 246 direct flights per week.

Weekly direct flights

MondaysTuesdaysWednesdaysThursdaysFridaysSaturdaysSundays
Direct flights6555655
Fly direct with

Allegiant Air on Mondays, and Fridays.

United Airlines on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays, Saturdays, and Sundays.

American Airlines on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays, Saturdays, and Sundays.

Check-in for a flight from Chicago to Knoxville

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
American AirlinesAALAAYesNo
United AirlinesUALUAYesNo
Delta Air LinesDALDLYesOpens 24 days before flight
Closes 1 hours before flight
Allegiant AirAAYG4NoOpens 24 days before flight
Closes 1 hours before flight
Spirit AirlinesNKSNKNoOpens 24 days before flight
Closes 1 hours before flight

Knoxville travel tips

1) Discover the ‘cradle of country music’

This is the name affectionately given to Knoxville as there are several country singers living in the area, and it has played a vital role in the development of country music. The fun way to learn all about country music is to join one of the ‘Cradle of Country Music’ walking tours. The tour reveals Knoxville’s links with Elvis, the Everly Brother, Dolly Parton, and many more. This is a self-guided walking tour and is free of charge.

2) Head for the caverns

Cherokee Caverns are a fun place to visit all year through as they comprise several ancient caves. The caverns were formed 300 million years ago when the area was submerged by the sea, and the evidence of cane torch marks show that they were used by early Indians. They were later discovered in 1854 by a local farmer. Today, the caverns become magical, though, in December when they are transformed into a pretty Christmas grotto and for other occasions, including Halloween.

3) Feast yourself Knoxville style

If you are spending time in the city, then it is an absolute ‘must’ to try some of the local specialities that are widely available in Knoxville restaurants. These tasty dishes include shrimp quesadillas, pesto grilled chicken club sliders, and wild mushroom stone-fired pizza. Filet mignon sandwich is a lunchtime special to try.

Learn more about COVID-19 restrictions in United States in our dedicated Stories article.

Frequently asked questions

How long does it take to travel from Chicago to Knoxville?
A one-way nonstop (direct) flight between Chicago and Knoxville takes around 1.7 hours.
What is the flight distance between Chicago and Knoxville?
The flight distance between Chicago and Knoxville is 740 km.
What airlines offer nonstop (direct) flights between Chicago and Knoxville?
Several carriers operate flights between Chicago and Knoxville. Airlines offering nonstop (direct) flights include United Airlines, Allegiant Air, American Airlines.
What are the most popular routes to and from Chicago?
Travelers frequently search for route combinations, such as Chicago and Las Vegas, Guadalajara, Denver, Orlando, Phoenix, Mexico City, Paris, Barcelona, Tampa, Miami, London, Rome, Los Angeles, Madrid, Fort Myers, Athens, San Francisco, New York, Austin, Atlanta.
What are the most popular routes to and from Knoxville?
Travelers frequently search for route combinations, such as Knoxville and New York, Denver, Las Vegas, Los Angeles, Orlando, Fort Lauderdale, Salt Lake City, Tampa, San Diego, San Francisco, Austin, San Juan, Portland, Boston, Sacramento, Seattle, Houston, Washington, D.C., Phoenix, West Palm Beach.
Which airports are there in Chicago?
Chicago is mainly served by O Hare International. But there are other airports nearby, including Chicago Midway International, Chicago Rockford International.
What airports are near Chicago?
The main airport in Chicago is O Hare International. It is also served by Gerald R. Ford International, General Mitchell International, General Wayne A. Downing Peoria International, Dane County Regional, Fort Wayne International, Central Illinois Regional, South Bend International, Quad City International, Kalamazoo/Battle Creek International, Decatur.
What airports are near Knoxville?
The main airport in Knoxville is McGhee Tyson. It is also served by Nashville International, McGhee Tyson, Asheville Regional, Greenville–Spartanburg International, Blue Grass, Chattanooga Metropolitan, Tri-Cities Regional.
What buses and trains depart from Chicago?
A number of bus and train companies depart from Chicago, including Amtrak train.
Is it possible to combine flights, buses, and trains in one itinerary when traveling between Chicago and Knoxville?
What is Virtual Interlining and how do I use it?
Which airlines fly between Chicago and Knoxville?
When's the best time to travel between Chicago and Knoxville?
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What time do flights between Chicago and Knoxville depart?
What time do flights between Chicago and Knoxville arrive?

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