Denver to Knoxville flights from $457

Flights starting at $457. Choose between Delta Air Lines, United Airlines, or American Airlines to find the best price.

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Travelers usually depart from Denver International, Denver Union Station, or Centennial Airport when they travel from Denver to Knoxville. Book your trip to arrive at McGhee Tyson, or Knoxville, TN - Greyhound Station. The distance between Denver and Knoxville is 1868 km. The most popular airlines for this route are Delta Air Lines, United Airlines, American Airlines, Allegiant Air, and Frontier Airlines. Denver and Knoxville have 202 direct flights per week.

Weekly direct flights

MondaysTuesdaysWednesdaysThursdaysFridaysSaturdaysSundays
Direct flights3223322
Fly direct with

Frontier Airlines on Mondays, Wednesdays, Fridays, and Saturdays.

Allegiant Air on Thursdays, and Sundays.

United Airlines on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays, Saturdays, and Sundays.

Check-in for a flight from Denver to Knoxville

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
Delta Air LinesDALDLYesOpens 24 days before flight
Closes 1 hours before flight
United AirlinesUALUAYesNo
American AirlinesAALAAYesNo
Allegiant AirAAYG4NoOpens 24 days before flight
Closes 1 hours before flight
Frontier AirlinesFFTF9NoOpens 24 days before flight
Closes 1 hours before flight

Knoxville travel tips

1) Hop on a trolley bus

The perfect way to explore downtown Knoxville is by trolley bus. There are three routes — the Green Line, Blue Line, and Orange Line, and all are very frequent. Trolley bus maps can be found in many locations. Services do not run on holidays or on UT home game Saturdays (football).

2) Jump on the free trolley

Jump on the free trolley from downtown to the Old City and enjoy a wander admiring the old architecture. Some of the old warehouses have been converted into microbreweries, and the old train depot is now a banqueting venue, while other buildings have been converted into galleries, restaurants and shops — breathing new life into this part of the city.

3) Delve into Knoxville’s history

To help you to understand the history of Knoxville history, a trip to the Beck Cultural Exchange is valuable. The focus here is on the local African American History, which is unique, and it is one of the largest museums of its kind. There are some fascinating photographs in its archives, and members of staff are on hand to answer any questions.

United States COVID-19 travel restrictions

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Latest COVID-19 restrictions

United States

Kiwi.com/COVID-19/United States
  • Travel is allowed

  • No proof of a negative pre-departure COVID-19 test required for vaccinated travelers

  • No quarantine required

Latest COVID-19 travel restrictions in United States – 06/2022
Your trip summary

Most travelers from Denver, DEN with proof of full COVID-19 vaccination can enter Knoxville, TYS.

Departure

Travel restrictions
  • Travel is allowed

  • No proof of a negative pre-departure COVID-19 test required for vaccinated travelers

  • No quarantine required

Return

Travel restrictions
  • Travel is allowed

  • No proof of a negative pre-departure COVID-19 test required for vaccinated travelers

  • No quarantine required

Information is provided as guidance only and accurate at the time of publishing. Always check government websites and airline materials before booking and traveling.

Learn more about COVID-19 restrictions in United States in our dedicated Stories article.

Frequently asked questions

How long does it take to travel from Denver to Knoxville?
A one-way nonstop (direct) flight between Denver and Knoxville takes around 3.0 hours.
What is the flight distance between Denver and Knoxville?
The flight distance between Denver and Knoxville is 1868 km.
What airlines offer nonstop (direct) flights between Denver and Knoxville?
Several carriers operate flights between Denver and Knoxville. Airlines offering nonstop (direct) flights include Allegiant Air, Frontier Airlines, United Airlines.
What are the most popular routes to and from Denver?
Travelers frequently search for route combinations, such as Denver and Las Vegas, Los Angeles, Chicago, Minneapolis, Dallas, Washington, D.C., Orlando, Phoenix, San Francisco, Houston, San Diego, Austin, Atlanta, Paris, Philadelphia, New York, Miami, London, Seattle, Tampa.
What are the most popular routes to and from Knoxville?
Travelers frequently search for route combinations, such as Knoxville and New York, Las Vegas, Los Angeles, Orlando, Fort Lauderdale, Salt Lake City, Tampa, San Diego, Chicago, San Francisco, Austin, San Juan, Portland, Boston, Sacramento, Seattle, Houston, Washington, D.C., Phoenix, West Palm Beach.
Which airports are there in Denver?
Denver is mainly served by Denver International. But there are other airports nearby, including Rocky Mountain Metropolitan Airport, Centennial Airport.
What airports are near Denver?
The main airport in Denver is Denver International. It is also served by Colorado Springs, Eagle County Regional, Pueblo Memorial, Laramie Regional, Cheyenne Regional.
What airports are near Knoxville?
The main airport in Knoxville is McGhee Tyson. It is also served by Nashville International, McGhee Tyson, Asheville Regional, Greenville–Spartanburg International, Blue Grass, Chattanooga Metropolitan, Tri-Cities Regional.
What buses and trains depart from Denver?
A number of bus and train companies depart from Denver, including Greyhound, Amtrak train.
Is it possible to combine flights, buses, and trains in one itinerary when traveling between Denver and Knoxville?
What is Virtual Interlining and how do I use it?
Which airlines fly between Denver and Knoxville?
When's the best time to travel between Denver and Knoxville?
What flights operate between Denver and Knoxville?
How many airports are there near Denver?
How many airports are there near Knoxville?
Is it possible to reach Denver by bus or train?
What time do nonstop (direct) flights between Denver and Knoxville depart?
What time do nonstop (direct) flights between Denver and Knoxville arrive?
What time do flights between Denver and Knoxville depart?
What time do flights between Denver and Knoxville arrive?

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