Cheap flights from Los Angeles to Knoxville from $272

Travelers frequently search for route combinations, such as Los Angeles and Guadalajara, Mexico City, Barcelona, Calgary, Toronto, New York, Dallas, Paris, San Francisco, Denver, Las Vegas, Rome, San Salvador, Cancún, Oaxaca, Athens, San José del Cabo, Honolulu, Edmonton, Istanbul.

Travelers frequently search for route combinations, such as Knoxville and Orlando, Boston, Tampa, Fort Lauderdale, Las Vegas, San Francisco, Chicago, Austin, Phoenix, Guatemala City, Denver, New York, Salt Lake City, St. Louis, Charlotte, Seattle, Richmond, London, Raleigh, Dallas.

The main airport in Los Angeles is Los Angeles International. It is also served by Tijuana International, San Diego International, John Wayne, Ontario International, Palm Springs International, Hollywood Burbank, Long Beach, Santa Barbara Municipal, Hawthorne Municipal, Meadows Field.

The main airport in Knoxville is McGhee Tyson. It is also served by Nashville International, Asheville Regional, McGhee Tyson, Greenville–Spartanburg International, Chattanooga Metropolitan, Blue Grass, Tri-Cities Regional.

Currently, you can fly between Los Angeles and Knoxville with United Airlines.

If you don’t have specific dates for your trip between Los Angeles and Knoxville, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Los Angeles and Knoxville, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Los Angeles. The main one is Los Angeles International and other nearby airports include Tijuana International, San Diego International, John Wayne, Ontario International, Palm Springs International, Hollywood Burbank, Long Beach, Santa Barbara Municipal, Hawthorne Municipal, Meadows Field

There are a number of airports in and around Knoxville. The main one is McGhee Tyson and other nearby airports include Nashville International, Asheville Regional, McGhee Tyson, Greenville–Spartanburg International, Chattanooga Metropolitan, Blue Grass, Tri-Cities Regional.