Cheap flights from San Francisco to Knoxville
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Cheap one-way trips starting from $ 56 from San Francisco SFO to Knoxville TYS
San Francisco InternationalMcGhee Tyson
One-way,
From $ 56
San Francisco InternationalMcGhee Tyson
One-way,
From $ 56
San Francisco InternationalMcGhee Tyson
One-way,
From $ 84
San Francisco InternationalMcGhee Tyson
One-way,
From $ 84
San Francisco InternationalMcGhee Tyson
One-way,
From $ 94
San Francisco InternationalMcGhee Tyson
One-way,
From $ 117
Cheap round trips starting from $ 99 from San Francisco SFO to Knoxville TYS
San Francisco InternationalMcGhee Tyson
Round trip, -
From $ 99
San Francisco InternationalMcGhee Tyson
Round trip, -
From $ 99
San Francisco InternationalMcGhee Tyson
Round trip, -
From $ 99
San Francisco InternationalMcGhee Tyson
Round trip, -
From $ 135
San Francisco InternationalMcGhee Tyson
Round trip, -
From $ 135
San Francisco InternationalMcGhee Tyson
Round trip, -
From $ 167
Travelers usually depart from San Francisco International, San Francisco, CA - Salesforce Plaza, or San Francisco, CA Train Station when they travel from San Francisco to Knoxville. Book your trip to arrive at McGhee Tyson, or Knoxville. The most popular airlines for this route are United Airlines, American Airlines, Allegiant Air, Delta Air Lines, and Frontier Airlines. San Francisco and Knoxville have 169 direct flights per week.
Weekly flights
| Mondays | Tuesdays | Wednesdays | Thursdays | Fridays | Saturdays | Sundays | |
|---|---|---|---|---|---|---|---|
| Number of flights | 19 | 18 | 51 | 30 | - | 25 | 26 |
Check-in for a flight from San Francisco to Knoxville
| Name | Carrier code | IATA Code | Passport needed during booking | Airport check-in closes | Online check-in available |
|---|---|---|---|---|---|
| United Airlines | UAL | UA | Yes | Unknown | No |
| American Airlines | AAL | AA | Yes | Unknown | No |
| Allegiant Air | AAY | G4 | No | 4 min before flight | No |
| Delta Air Lines | DAL | DL | Yes | Unknown | No |
| Frontier Airlines | FFT | F9 | No | Unknown | No |
Frequently asked questions
What are the most popular routes to and from San Francisco?
Travelers frequently search for route combinations, such as San Francisco and McCarran International, Los Angeles International, Fort Lauderdale–Hollywood International, Denver International, Phoenix Sky Harbor International, Dallas/Fort Worth International, Seattle–Tacoma International, Salt Lake City International, San Diego International, Philadelphia International, Portland International.
What are the most popular routes to and from Knoxville?
Travelers frequently search for route combinations, such as Knoxville and Orlando Sanford International, Newark Liberty International, Fort Lauderdale–Hollywood International, Denver International, St. Pete–Clearwater International, William P. Hobby, O Hare International, Logan International, Sarasota–Bradenton International, Punta Gorda, Blue Grass.
What buses and trains depart from San Francisco?
A number of bus and train companies depart from San Francisco, including Greyhound.
Is it possible to combine flights, buses, and trains in one itinerary when traveling between San Francisco and Knoxville?
What is Virtual Interlining and how do I use it?
Which airlines fly between San Francisco and Knoxville?
When's the best time to travel between San Francisco and Knoxville?
What flights operate between San Francisco and Knoxville?
Is it possible to reach San Francisco by bus or train?
What time do nonstop (direct) flights between San Francisco and Knoxville depart?
What time do nonstop (direct) flights between San Francisco and Knoxville arrive?
What time do flights between San Francisco and Knoxville depart?
What time do flights between San Francisco and Knoxville arrive?
Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any A and any B in the world by plane, train, and bus. Find the cheapest routes and best deals for you, as well as the best dates on which to travel.
Explore alternative destinations
Flights from San Francisco
- Flights from San Francisco to McCarran International
- Flights from San Francisco to Los Angeles International
- Flights from San Francisco to Fort Lauderdale–Hollywood International
- Flights from San Francisco to Denver International
- Flights from San Francisco to Phoenix Sky Harbor International
- Flights from San Francisco to Dallas/Fort Worth International
- Flights from San Francisco to Seattle–Tacoma International
- Flights from San Francisco to Salt Lake City International
- Flights from San Francisco to San Diego International
- Flights from San Francisco to Philadelphia International
- Flights from San Francisco to Portland International
Flights to Knoxville
- Flights from Orlando Sanford International to Knoxville
- Flights from Newark Liberty International to Knoxville
- Flights from Fort Lauderdale–Hollywood International to Knoxville
- Flights from Denver International to Knoxville
- Flights from St. Pete–Clearwater International to Knoxville
- Flights from William P. Hobby to Knoxville
- Flights from O Hare International to Knoxville
- Flights from Logan International to Knoxville
- Flights from Sarasota–Bradenton International to Knoxville
- Flights from Punta Gorda to Knoxville
- Flights from Blue Grass to Knoxville
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