Cheap flights from Des Moines to Columbus from $173

Travelers frequently search for route combinations, such as Des Moines and Las Vegas, Nashville, Phoenix, Austin, Santa Ana, Orlando, Mexico City, Tampa, Boston, Malé, Montreal, Sacramento, Guadalajara, New York, Shanghai, Winnipeg, Houston, San Pedro Sula, Vancouver, Kathmandu.

Travelers frequently search for route combinations, such as Columbus and New York, Orlando, Fort Lauderdale, Raleigh, Los Angeles, Tampa, Fort Myers, New Orleans, London, Paris, Dallas, Las Vegas, Mexico City, Sarasota, Seattle, Punta Gorda, Boston, Medellín, Hartford, Edmonton.

The main airport in Des Moines is Des Moines International. It is also served by Des Moines International, Eppley Airfield, The Eastern Iowa, Sioux Gateway, Kirksville Regional, Southeast Iowa Regional, Fort Dodge Regional, Mason City Municipal, Waterloo Regional.

The main airport in Columbus is John Glenn Columbus International. It is also served by Cleveland Hopkins International, Cincinnati/Northern Kentucky International, Pittsburgh International, Akron–Canton, Fort Wayne International, Yeager, Toledo Express, Tri-State, Dayton International, North Central West Virginia.

Currently, you can fly between Des Moines and Columbus with Allegiant Air, United Airlines, Spirit Airlines, Frontier Airlines, BREEZE.

If you don’t have specific dates for your trip between Des Moines and Columbus, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Des Moines and Columbus, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Des Moines. The main one is Des Moines International and other nearby airports include Des Moines International, Eppley Airfield, The Eastern Iowa, Sioux Gateway, Kirksville Regional, Southeast Iowa Regional, Fort Dodge Regional, Mason City Municipal, Waterloo Regional

There are a number of airports in and around Columbus. The main one is John Glenn Columbus International and other nearby airports include Cleveland Hopkins International, Cincinnati/Northern Kentucky International, Pittsburgh International, Akron–Canton, Fort Wayne International, Yeager, Toledo Express, Tri-State, Dayton International, North Central West Virginia.