Cheap flights from Des Moines to Florence from $486

Travelers frequently search for route combinations, such as Des Moines and Las Vegas, Nashville, Phoenix, Austin, Santa Ana, Orlando, Mexico City, Tampa, Boston, Malé, Montreal, Sacramento, Guadalajara, New York, Shanghai, Winnipeg, Houston, San Pedro Sula, Vancouver, Kathmandu.

Travelers frequently search for route combinations, such as Florence and New York, Orlando, Miami, Los Angeles, Boston, Tampa, San Francisco, San Diego, Denver, Barcelona, Dallas, London, Cleveland, Las Vegas, Washington, D.C., Detroit, Atlanta, Paris, Madrid, Amsterdam.

The main airport in Des Moines is Des Moines International. It is also served by Des Moines International, Eppley Airfield, The Eastern Iowa, Southeast Iowa Regional, Waterloo Regional, Fort Dodge Regional, Mason City Municipal, Sioux Gateway.

The main airport in Florence is Florence. It is also served by Leonardo da Vinci–Fiumicino Airport, Milan Bergamo International Airport, Venice Marco Polo, Bologna Guglielmo Marconi, Florence, Ciampino–G. B. Pastine International, Treviso, Pisa International, Linate, Verona Villafranca.

Currently, you can fly between Des Moines and Florence with Vueling, United Airlines, KLM Royal Dutch Airlines, Air France.

If you don’t have specific dates for your trip between Des Moines and Florence, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Des Moines and Florence, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Des Moines. The main one is Des Moines International and other nearby airports include Des Moines International, Eppley Airfield, The Eastern Iowa, Southeast Iowa Regional, Waterloo Regional, Fort Dodge Regional, Mason City Municipal, Sioux Gateway

There are a number of airports in and around Florence. The main one is Florence and other nearby airports include Leonardo da Vinci–Fiumicino Airport, Milan Bergamo International Airport, Venice Marco Polo, Bologna Guglielmo Marconi, Florence, Ciampino–G. B. Pastine International, Treviso, Pisa International, Linate, Verona Villafranca.