Cheap flights from Des Moines to Los Angeles from $280

Travelers frequently search for route combinations, such as Des Moines and Phoenix, Fort Lauderdale, Orlando, New York, Salt Lake City, Miami, Mexico City, Las Vegas, San Francisco, Milan, Santa Ana, Washington, D.C., San Diego, Boston, Punta Gorda, London, León, Toronto, Paris, Tampa.

Travelers frequently search for route combinations, such as Los Angeles and Guadalajara, Mexico City, San Francisco, Denver, New York, Dallas, Barcelona, Las Vegas, Rome, London, Atlanta, Portland, Chicago, Washington, D.C., Toronto, Cancún, Calgary, Paris, Seattle, San José del Cabo.

The main airport in Des Moines is Des Moines International. It is also served by Eppley Airfield, Des Moines International, The Eastern Iowa, Fort Dodge Regional, Mason City Municipal, Waterloo Regional, Kirksville Regional, Southeast Iowa Regional, Sioux Gateway.

The main airport in Los Angeles is Los Angeles International. It is also served by Tijuana International, San Diego International, Ontario International, John Wayne, Palm Springs International, Hollywood Burbank, Long Beach, Santa Maria Public, Santa Barbara Municipal, Meadows Field.

Currently, you can fly between Des Moines and Los Angeles with United Airlines, American Airlines.

If you don’t have specific dates for your trip between Des Moines and Los Angeles, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Des Moines and Los Angeles, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Des Moines. The main one is Des Moines International and other nearby airports include Eppley Airfield, Des Moines International, The Eastern Iowa, Fort Dodge Regional, Mason City Municipal, Waterloo Regional, Kirksville Regional, Southeast Iowa Regional, Sioux Gateway

There are a number of airports in and around Los Angeles. The main one is Los Angeles International and other nearby airports include Tijuana International, San Diego International, Ontario International, John Wayne, Palm Springs International, Hollywood Burbank, Long Beach, Santa Maria Public, Santa Barbara Municipal, Meadows Field.