Cheap flights from Des Moines, IA to San Diego, CA

Flights starting at $55. Choose between United Airlines, Frontier Airlines, or Spirit Airlines to find the best price.

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Des Moines DSMDenver DENPhoenix PHXDes Moines DSM
$267
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Des Moines DSMDenver DENPhoenix PHXDes Moines DSM
$209
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Book your trip to arrive at San Diego International, San Diego, CA - Old Town, San Diego, CA - La Jolla, San Diego, CA - Santa Fe, or San Diego, CA Bus Station. The most popular airlines for this route are United Airlines, Frontier Airlines, Spirit Airlines, American Airlines, and Allegiant Air. Des Moines and San Diego have 316 direct flights per week.

Check-in for a flight from Des Moines to San Diego

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
United AirlinesUALUAYesNo
Frontier AirlinesFFTF9NoOpens 24 days before flight
Closes 1 hours before flight
Spirit AirlinesNKSNKNoOpens 24 days before flight
Closes 1 hours before flight
American AirlinesAALAANoNo
Allegiant AirAAYG4NoOpens 24 days before flight
Closes 1 hours before flight
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Frequently asked questions

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Is it possible to combine flights, buses, and trains in one itinerary when traveling between Des Moines and San Diego?
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What time do nonstop (direct) flights between Des Moines and San Diego depart?
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What time do flights between Des Moines and San Diego depart?
What time do flights between Des Moines and San Diego arrive?

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