Cheap flights from Des Moines to São Paulo from $392

Travelers frequently search for route combinations, such as Des Moines and Las Vegas, Nashville, Phoenix, Austin, Santa Ana, Orlando, Mexico City, Tampa, Boston, Malé, Montreal, Sacramento, Guadalajara, New York, Shanghai, Winnipeg, Houston, San Pedro Sula, Vancouver, Kathmandu.

Travelers frequently search for route combinations, such as São Paulo and Atlanta, Los Angeles, Fort Lauderdale, New York, San Francisco, Orlando, Denver, Boston, Washington, D.C., Detroit, Houston, Rio de Janeiro, Chicago, Columbus, Phoenix, Minneapolis, Miami, Austin, Nashville, San Juan.

The main airport in Des Moines is Des Moines International. It is also served by Des Moines International, Eppley Airfield, The Eastern Iowa, Southeast Iowa Regional, Kirksville Regional, Mason City Municipal, Sioux Gateway, Fort Dodge Regional, Waterloo Regional.

The main airport in São Paulo is São Paulo–Guarulhos International. It is also served by Aeroporto Internacional de São José dos Campos.

Currently, you can fly between Des Moines and São Paulo with Allegiant Air, Copa Airlines, Gol Transportes Aéreos, LATAM Airlines, Azul.

If you don’t have specific dates for your trip between Des Moines and São Paulo, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Des Moines and São Paulo, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Des Moines. The main one is Des Moines International and other nearby airports include Des Moines International, Eppley Airfield, The Eastern Iowa, Southeast Iowa Regional, Kirksville Regional, Mason City Municipal, Sioux Gateway, Fort Dodge Regional, Waterloo Regional

There are a number of airports in and around São Paulo. The main one is São Paulo–Guarulhos International and other nearby airports include Aeroporto Internacional de São José dos Campos.