Cheap flights from Des Moines to St. Louis
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Cheap one-way trips starting from $ 109 from Des Moines DSM to St. Louis STL
Des Moines InternationalSt. Louis Lambert International
One-way,
From $ 109
Des Moines InternationalSt. Louis Lambert International
One-way,
From $ 109
Des Moines InternationalSt. Louis Lambert International
One-way,
From $ 109
Des Moines InternationalSt. Louis Lambert International
One-way,
From $ 109
Des Moines InternationalSt. Louis Lambert International
One-way,
From $ 109
Des Moines InternationalSt. Louis Lambert International
One-way,
From $ 109
Cheap round trips starting from $ 198 from Des Moines DSM to St. Louis STL
Des Moines InternationalSt. Louis Lambert International
Round trip, -
From $ 198
Des Moines InternationalSt. Louis Lambert International
Round trip, -
From $ 198
Des Moines InternationalSt. Louis Lambert International
Round trip, -
From $ 198
Des Moines InternationalSt. Louis Lambert International
Round trip, -
From $ 217
Des Moines InternationalSt. Louis Lambert International
Round trip, -
From $ 217
Des Moines InternationalSt. Louis Lambert International
Round trip, -
From $ 217
Travelers usually depart from Des Moines International, or Des Moines when they travel from Des Moines to St. Louis. Book your trip to arrive at St. Louis Lambert International, or St. Louis Union Station. The distance between Des Moines and St. Louis is 417 km. The most popular airlines for this route are United Airlines, American Airlines, Allegiant Air, WN, and Delta Air Lines. Des Moines and St. Louis have 161 direct flights per week.
Weekly flights
| Mondays | Tuesdays | Wednesdays | Thursdays | Fridays | Saturdays | Sundays | |
|---|---|---|---|---|---|---|---|
| Number of flights | 75 | 19 | 16 | 23 | - | 14 | 14 |
Fly direct with
WN on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays, Saturdays, and Sundays.
Check-in for a flight from Des Moines to St. Louis
| Name | Carrier code | IATA Code | Passport needed during booking | Airport check-in closes | Online check-in available |
|---|---|---|---|---|---|
| United Airlines | UAL | UA | Yes | Unknown | No |
| American Airlines | AAL | AA | Yes | Unknown | No |
| Allegiant Air | AAY | G4 | No | 4 min before flight | No |
| WN | SWA | WN | No | Unknown | No |
| Delta Air Lines | DAL | DL | Yes | Unknown | No |
Frequently asked questions
How long does it take to travel from Des Moines to St. Louis?
A one-way nonstop (direct) flight between Des Moines and St. Louis takes around 1.2 hours.
What is the flight distance between Des Moines and St. Louis?
The flight distance between Des Moines and St. Louis is 417 km.
What airlines offer nonstop (direct) flights between Des Moines and St. Louis?
Several carriers operate flights between Des Moines and St. Louis. Airlines offering nonstop (direct) flights include WN.
What are the most popular routes to and from Des Moines?
Travelers frequently search for route combinations, such as Des Moines and Orlando Sanford International, Miami International, Phoenix–Mesa Gateway, Denver International, San Francisco International, Salt Lake City International, Southwest Florida International, Nashville International, Raleigh–Durham International, Ontario International, Hector International.
What are the most popular routes to and from St. Louis?
Travelers frequently search for route combinations, such as St. Louis and Denver International, Charlotte Douglas International, Sacramento International, Indianapolis International, Clinton National, Wichita Dwight D. Eisenhower National, Owensboro–Daviess County Regional, Jonesboro Municipal, Williamson County Regional, Quincy Regional, Waynesville-St. Robert Regional.
What buses and trains depart from Des Moines?
A number of bus and train companies depart from Des Moines, including Jefferson Lines.
Is it possible to combine flights, buses, and trains in one itinerary when traveling between Des Moines and St. Louis?
What is Virtual Interlining and how do I use it?
Which airlines fly between Des Moines and St. Louis?
When's the best time to travel between Des Moines and St. Louis?
What flights operate between Des Moines and St. Louis?
Is it possible to reach Des Moines by bus or train?
What time do nonstop (direct) flights between Des Moines and St. Louis depart?
What time do nonstop (direct) flights between Des Moines and St. Louis arrive?
What time do flights between Des Moines and St. Louis depart?
What time do flights between Des Moines and St. Louis arrive?
Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any A and any B in the world by plane, train, and bus. Find the cheapest routes and best deals for you, as well as the best dates on which to travel.
Explore alternative destinations
Flights from Des Moines
- Flights from Des Moines to Orlando Sanford International
- Flights from Des Moines to Miami International
- Flights from Des Moines to Phoenix–Mesa Gateway
- Flights from Des Moines to Denver International
- Flights from Des Moines to San Francisco International
- Flights from Des Moines to Salt Lake City International
- Flights from Des Moines to Southwest Florida International
- Flights from Des Moines to Nashville International
- Flights from Des Moines to Raleigh–Durham International
- Flights from Des Moines to Ontario International
- Flights from Des Moines to Hector International
Flights to St. Louis
- Flights from Denver International to St. Louis
- Flights from Charlotte Douglas International to St. Louis
- Flights from Sacramento International to St. Louis
- Flights from Indianapolis International to St. Louis
- Flights from Clinton National to St. Louis
- Flights from Wichita Dwight D. Eisenhower National to St. Louis
- Flights from Owensboro–Daviess County Regional to St. Louis
- Flights from Jonesboro Municipal to St. Louis
- Flights from Williamson County Regional to St. Louis
- Flights from Quincy Regional to St. Louis
- Flights from Waynesville-St. Robert Regional to St. Louis
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