Cheap flights from Knoxville, TN to La Serena, Chile

Travelers frequently search for route combinations, such as Knoxville and Denver, Las Vegas, New York, Orlando, Los Angeles, Fort Lauderdale, Salt Lake City, Chicago, San Francisco, Houston, Sacramento, Boston, Minneapolis, Tampa, London, San Juan, Phoenix, Dallas, San Diego, Destin.

Travelers frequently search for route combinations, such as La Serena and Santiago de Chile, Lima, Antofagasta, Iquique, Cusco, Calama, Concepción, Fort Lauderdale, Los Angeles, Tijuana, Punta Arenas, Mendoza, Arica, San José, Buenos Aires, Geneva, Puerto Montt, Tallinn, Richmond, Minneapolis.

The main airport in Knoxville is McGhee Tyson. It is also served by Nashville International, Asheville Regional, McGhee Tyson, Greenville–Spartanburg International, Blue Grass, Chattanooga Metropolitan, Tri-Cities Regional.

The main airport in La Serena is La Florida. It is also served by La Florida.

Yes, it's possible to combine different modes of transport between Knoxville and La Serena thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between Knoxville and La Serena can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.

Virtual Interlining provides a revolutionary way of traveling. You can combine different modes of transport like flights, trains, and buses into one itinerary. And this often saves money. Thanks to the world's largest carrier database, the Kiwi.com search function enables anyone to mix and match different modes of transport easily.

Currently, you can fly between Knoxville and La Serena with Allegiant Air, LATAM Airlines, Avianca, JetSMART, JetBlue Airways.

If you don’t have specific dates for your trip between Knoxville and La Serena, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Knoxville and La Serena, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What's more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.