Cheap flights from Mexico City to Panama City from $472

Travelers frequently search for route combinations, such as Mexico City and Chicago, Atlanta, Los Angeles, Houston, San Francisco, Miami, Dallas, Seattle, Denver, New York, Minneapolis, Oakland, Orlando, Salt Lake City, San Antonio, Detroit, Las Vegas, Washington, D.C., Philadelphia, Portland.

Travelers frequently search for route combinations, such as Panama City and Philadelphia, Atlanta, Istanbul, Richmond, Grand Rapids, Omaha, Nashville, Hartford, Guadalajara, Bismarck, Sioux Falls, Fargo, Cincinnati, Phoenix, Tucson, Columbus, Reno, Boston, Albany, Milwaukee.

The main airport in Mexico City is Mexico City International. It is also served by Mexico City International, Morelia International, Querétaro International, Puebla International, Toluca International.

The main airport in Panama City is Northwest Florida Beaches International. It is also served by Pensacola International, Destin–Fort Walton Beach, Tallahassee International, Southwest Georgia Regional, Montgomery Regional, Valdosta Regional, Dothan Regional.

Currently, you can fly between Mexico City and Panama City with WestJet, United Airlines, Air Canada, VivaAerobus, AeroMexico.

If you don’t have specific dates for your trip between Mexico City and Panama City, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Mexico City and Panama City, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Mexico City. The main one is Mexico City International and other nearby airports include Mexico City International, Morelia International, Querétaro International, Puebla International, Toluca International

There are a number of airports in and around Panama City. The main one is Northwest Florida Beaches International and other nearby airports include Pensacola International, Destin–Fort Walton Beach, Tallahassee International, Southwest Georgia Regional, Montgomery Regional, Valdosta Regional, Dothan Regional.